[HTML][HTML] Viscoelasticity imaging of biological tissues and single cells using shear wave propagation

H Li, G Flé, M Bhatt, Z Qu, S Ghazavi, L Yazdani… - Frontiers in …, 2021 - frontiersin.org
Changes in biomechanical properties of biological soft tissues are often associated with
physiological dysfunctions. Since biological soft tissues are hydrated, viscoelasticity is likely …

[HTML][HTML] Accuracy of Transient Elastography in Assessing Fibrosis at Diagnosis in Naïve Patients With Primary Biliary Cholangitis: A Dual Cut‐Off Approach

L Cristoferi, V Calvaruso, D Overi, M Viganò… - Hepatology, 2021 - journals.lww.com
Conclusions In a multicenter study of treatment‐naïve PBC patients, we identified two cutoffs
(LSM≤ 6.5 and> 11.0 kPa) able to discriminate at diagnosis the absence or presence …

Measurement of liver and spleen stiffness as complementary methods for assessment of liver fibrosis in autoimmune hepatitis

MK Janik, B Kruk, B Szczepankiewicz… - Liver …, 2021 - Wiley Online Library
Abstract Background and Aims Liver stiffness measurements (LSM), commonly performed
by transient elastography (TE) or two‐dimensional shear wave elastography (2D‐SWE), are …

Hepatic differentiation of human embryonic stem cells by coupling substrate stiffness and microtopography

C Luo, D Lü, L Zheng, F Zhang, X Zhang, S Lü… - Biomaterials …, 2021 - pubs.rsc.org
Mechanical or physical cues are associated with the growth and differentiation of embryonic
stem cells (ESCs). While the substrate stiffness or topography independently affects the …

[HTML][HTML] Shear wave-based sound touch elastography in liver fibrosis assessment for patients with autoimmune liver diseases

L Yang, W Ling, D He, C Lu, L Ma, L Tang… - … Imaging in Medicine …, 2021 - ncbi.nlm.nih.gov
Background Shear wave-based ultrasonic elastography (USE) has been widely used for the
assessment of liver fibrosis in patients with chronic liver diseases (CLD). However …

[HTML][HTML] Identification of miR-199a-5p, miR-214-3p and miR-99b-5p as fibrosis-specific extracellular biomarkers and promoters of HSC activation

CJ Messner, S Schmidt, D Özkul, C Gaiser… - International Journal of …, 2021 - mdpi.com
Liver fibrosis is characterized by the accumulation of extracellular matrix (ECM) resulting in
the formation of fibrous scars. In the clinic, liver biopsies are the standard diagnostic method …

FIB-4 and APRI scores for predicting severe liver fibrosis in chronic hepatitis HCV patients: a monocentric retrospective study

R Catanzaro, A Aleo, M Sciuto, L Zanoli… - Clinical and …, 2021 - termedia.pl
Results Twenty-six patients (24.52%) had F4 fibrosis, 80 patients (75.48%) had non-F4
fibrosis (F0-F3). There was a statistically significant difference (p< 0.05) between non-F4 …

[HTML][HTML] Exploring interactions between primary hepatocytes and non-parenchymal cells on physiological and pathological liver stiffness

V Natarajan, Y Moeun, S Kidambi - Biology, 2021 - mdpi.com
Simple Summary Chronic liver disease is characterized by progressive hepatic fibrosis
leading to the formation of cirrhosis irrespective of the etiology with no effective treatment …

[HTML][HTML] A non-invasive model for predicting liver inflammation in chronic hepatitis B patients with normal serum alanine aminotransferase levels

X Li, Y Xing, D Zhou, H Xiao, Z Zhou, Z Han… - Frontiers in …, 2021 - frontiersin.org
Background and Aims: Chronic hepatitis B (CHB) patients with normal alanine
aminotransferase (ALT) levels are at risk of disease progression. Currently, liver biopsy is …

[HTML][HTML] Elastography improves accuracy of early hepato-biliary complications diagnosis after allogeneic stem cell transplantation

PE Debureaux, P Bourrier, PE Rautou… - …, 2021 - ncbi.nlm.nih.gov
Significant morbidity and mortality have been associated with liver complications after
allogeneic hematopoietic stem cell transplantation (allo-HSCT). Causes and consequences …