[HTML][HTML] Activatable fluorescence sensors for in vivo bio-detection in the second near-infrared window

M Zhao, B Li, H Zhang, F Zhang - Chemical Science, 2021 - pubs.rsc.org
Fluorescence imaging in the second near-infrared (NIR-II, 1000–1700 nm) window has
exhibited advantages of high optical resolution at deeper penetration (ca. 5–20 mm) in bio …

Diagnostics for wound infections

S Li, P Renick, J Senkowsky, A Nair… - Advances in wound …, 2021 - liebertpub.com
Significance: Infections can significantly delay the healing process in chronic wounds,
placing an enormous economic burden on health care resources. Identification of infection …

[HTML][HTML] Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment

A Nicolas-Boluda, J Vaquero, L Vimeux, T Guilbert… - Elife, 2021 - elifesciences.org
Only a fraction of cancer patients benefits from immune checkpoint inhibitors. This may be
partly due to the dense extracellular matrix (ECM) that forms a barrier for T cells. Comparing …

Noninvasive Cancer Diagnosis In Vivo Based on a Viscosity-Activated Near-Infrared Fluorescent Probe

J Yin, X Kong, W Lin - Analytical Chemistry, 2021 - ACS Publications
Effective and noninvasive cancer diagnosis is expected to ease the burden of continued
increased deaths worldwide. Herein, we proposed viscosity of the tumor microenvironment …

[HTML][HTML] Evaluation of wavelength ranges and tissue depth probed by diffuse reflectance spectroscopy for colorectal cancer detection

MS Nogueira, S Maryam, M Amissah, H Lu, N Lynch… - Scientific Reports, 2021 - nature.com
Colorectal cancer (CRC) is the third most common type of cancer worldwide and the second
most deadly. Recent research efforts have focused on developing non-invasive techniques …

Autofluorescence of blood and its application in biomedical and clinical research

AB Shrirao, RS Schloss, Z Fritz… - Biotechnology and …, 2021 - Wiley Online Library
Autofluorescence of blood has been explored as a label free approach for detection of cell
types, as well as for diagnosis and detection of infection, cancer, and other diseases …

Mesoscopic fluorescence lifetime imaging: Fundamental principles, clinical applications and future directions

A Alfonso‐Garcia, J Bec, B Weyers… - Journal of …, 2021 - Wiley Online Library
Fluorescence lifetime imaging (FLIm) is an optical spectroscopic imaging technique capable
of real‐time assessments of tissue properties in clinical settings. Label‐free FLIm is sensitive …

Fast label-free identification of bacteria by synchronous fluorescence of amino acids

Y Shlosberg, Y Farber, S Hasson, V Bulatov… - Analytical and …, 2021 - Springer
Fast identification of pathogenic bacteria is an essential need for patient's diagnostic in
hospitals and environmental monitoring of water and air quality. Bacterial cells consist of a …

Nonlinear and vibrational microscopy for label-free characterization of amyloid-β plaques in Alzheimer's disease model

R Cunha, L Lafeta, EA Fonseca, A Barbosa… - Analyst, 2021 - pubs.rsc.org
Given the long subclinical stage of Alzheimer's disease (AD), the study of biomarkers is
relevant both for early diagnosis and the fundamental understanding of the pathophysiology …

Thermal analysis of laser irradiation-gold nanorod combinations at 808 nm, 940 nm, 975 nm and 1064 nm wavelengths in breast cancer model

L Bianchi, R Mooney, YR Cornejo… - International Journal …, 2021 - Taylor & Francis
Background Photothermal therapy is currently under the spotlight to improve the efficacy of
minimally invasive thermal treatment of solid tumors. The interplay of several factors …