Tumor microenvironment and immune evasion in head and neck squamous cell carcinoma
A Elmusrati, J Wang, CY Wang - International journal of oral science, 2021 - nature.com
Head and neck squamous cell carcinoma (HNSCC), an aggressive malignancy, is
characterized by high morbidity and low survival rates with limited therapeutic options …
characterized by high morbidity and low survival rates with limited therapeutic options …
Tumor microenvironment: an evil nexus promoting aggressive head and neck squamous cell carcinoma and avenue for targeted therapy
Head and neck squamous cell carcinoma (HNSCC) is a very aggressive disease with a poor
prognosis for advanced-stage tumors. Recent clinical, genomic, and cellular studies have …
prognosis for advanced-stage tumors. Recent clinical, genomic, and cellular studies have …
Anti–PD-1 and anti–PD-L1 in head and neck cancer: a network meta-analysis
A Botticelli, A Cirillo, L Strigari, F Valentini… - Frontiers in …, 2021 - frontiersin.org
Objective The monoclonal antibodies anti-programmed death protein-1 (anti–PD-1)
nivolumab and pembrolizumab are the first immune checkpoint inhibitors (ICIs) approved for …
nivolumab and pembrolizumab are the first immune checkpoint inhibitors (ICIs) approved for …
The key differences between human papillomavirus-positive and-negative head and neck cancers: biological and clinical implications
SF Powell, L Vu, WC Spanos, D Pyeon - Cancers, 2021 - mdpi.com
Simple Summary Head and neck cancer (HNC) is the sixth most common cancer, causing
almost half a million deaths worldwide every year. The two subtypes of HNC are distinctly …
almost half a million deaths worldwide every year. The two subtypes of HNC are distinctly …
Tumor microenvironment and immune-related therapies of head and neck squamous cell carcinoma
Y Qin, X Zheng, W Gao, B Wang, Y Wu - Molecular Therapy-Oncolytics, 2021 - cell.com
Head and neck squamous cell carcinomas (HNSCCs) are a type of common malignant
tumor, mainly manifesting as oropharyngeal, oral cavity, laryngopharyngeal …
tumor, mainly manifesting as oropharyngeal, oral cavity, laryngopharyngeal …
Precision medicine approaches to overcome resistance to therapy in head and neck cancers
S Ortiz-Cuaran, J Bouaoud, A Karabajakian… - Frontiers in …, 2021 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) is the sixth most incident cancer
worldwide. More than half of HNSCC patients experience locoregional or distant relapse to …
worldwide. More than half of HNSCC patients experience locoregional or distant relapse to …
Tumor microenvironment and Oral Squamous Cell Carcinoma: A crosstalk between the inflammatory state and tumor cell migration
Objectives To analyze the inflammatory millieu in oral squamous cell carcinoma (OSCC)
tumors and the influence of macrophages related-cytokines on the tumor cell migration …
tumors and the influence of macrophages related-cytokines on the tumor cell migration …
Primary head and neck tumour-derived fibroblasts promote lymphangiogenesis in a lymphatic organotypic co-culture model
Background In head and neck cancer, intratumour lymphatic density and tumour
lymphangiogenesis have been correlated with lymphatic metastasis, making …
lymphangiogenesis have been correlated with lymphatic metastasis, making …
Vaccine-based immunotherapy for head and neck cancers
S Beyaert, JP Machiels, S Schmitz - Cancers, 2021 - mdpi.com
Simple Summary Therapeutic vaccines are given to patients with cancer, as opposed to
prophylactic vaccines given to a healthy population. The challenge for therapeutic …
prophylactic vaccines given to a healthy population. The challenge for therapeutic …
Epithelial–Mesenchymal Transition Associated with Head and Neck Squamous Cell Carcinomas: A Review
R González-González, G Ortiz-Sarabia… - Cancers, 2021 - mdpi.com
Simple Summary Mesenchymal conversion occurring in malignant epithelial neoplasms is
undesirable in tumors since it promotes more aggressive tumor behavior. This phenomenon …
undesirable in tumors since it promotes more aggressive tumor behavior. This phenomenon …