[HTML][HTML] Humanized neurofibroma model from induced pluripotent stem cells delineates tumor pathogenesis and developmental origins

J Mo, C Anastasaki, Z Chen, T Shipman… - The Journal of …, 2021 - Am Soc Clin Investig
Neurofibromatosis type 1 (NF1) is a common tumor predisposition syndrome caused by NF1
gene mutation, in which affected patients develop Schwann cell lineage peripheral nerve …

Seq your destiny: neural crest fate determination in the genomic era

S Gandhi, ME Bronner - Annual Review of Genetics, 2021 - annualreviews.org
Neural crest stem/progenitor cells arise early during vertebrate embryogenesis at the border
of the forming central nervous system. They subsequently migrate throughout the body …

Phenotypic and functional comparison of rat enteric neural crest-derived cells during fetal and early-postnatal stages

DH Tian, CH Qin, WY Xu, WK Pan… - Neural Regeneration …, 2021 - journals.lww.com
In our previous study, we showed that with increasing time in culture, the growth
characteristics of enteric neural crest-derived cells (ENCCs) change, and that the …

胚胎和产后早期大鼠肠神经嵴前体细胞表型和功能的比较研究

DH Tian, CH Qin, WY Xu, WK Pan, YY Zhao… - 中国神经再生研究 …, 2021 - sjzsyj.com.cn
作者既往研究显示, 随着培养时间的延长, 肠神经嵴前体细胞的生长特征会发生变化,
且体外培养的产后肠神经嵴前体细胞的增殖, 迁移和神经分化潜能明显降低 …