Novel use of low-dose radiotherapy to modulate the tumor microenvironment of liver metastases

K He, HB Barsoumian, G Bertolet, V Verma… - Frontiers in …, 2021 - frontiersin.org
Despite multiple therapeutic approaches, the presence of liver metastases carries a guarded
prognosis, urgently necessitating further clinical and scientific research to develop curative …

High-dose irradiation in combination with non-ablative low-dose radiation to treat metastatic disease after progression on immunotherapy: Results of a phase II trial

RR Patel, K He, HB Barsoumian, JY Chang… - Radiotherapy and …, 2021 - Elsevier
Aim To report early findings from a phase II trial of high-dose radiotherapy (HD-RT) with or
without low-dose RT (LD-RT) for metastatic cancer. Methods Eligible patients had metastatic …

Group phenotypic composition in cancer

JP Capp, J DeGregori, AM Nedelcu, AM Dujon… - Elife, 2021 - elifesciences.org
Although individual cancer cells are generally considered the Darwinian units of selection in
malignant populations, they frequently act as members of groups where fitness of the group …

Immunotherapy combined with high-and low-dose radiation to all sites leads to complete clearance of disease in a patient with metastatic vaginal melanoma

D Sezen, RR Patel, C Tang, M Onstad, P Nagarajan… - Gynecologic …, 2021 - Elsevier
A 73-year-old woman with metastatic vaginal mucosal melanoma that had progressed on
ipilimumab and nivolumab experienced clinical and radiographic complete response to dual …

[HTML][HTML] Thoracic stereotactic body radiation therapy plus first-line tyrosine kinase inhibitors for patients with epidermal growth factor receptor-mutant polymetastatic …

X Wang, Z Lu, Z Zeng, J Cai, P Xu, A Liu - Medicine, 2021 - journals.lww.com
The role of thoracic stereotactic body radiation therapy (SBRT) in addition to epidermal
growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in EGFR-mutant …

OLIGO-AIRO: a national survey on the role of radiation oncologist in the management of OLIGO-metastatic patients on the behalf of AIRO

R Mazzola, BA Jereczek-Fossa, P Antognoni… - Medical Oncology, 2021 - Springer
In the last years, several evidences demonstrated the role of stereotactic body radiotherapy
(SBRT) in the oligometastatic disease and the possibility to increase survival in selected …

Group phenotypic composition in cancer

C Jean-Pascal, J DeGregori, AM Nedelcu, AM Dujon… - eLife, 2021 - search.proquest.com
Although individual cancer cells are generally considered the Darwinian units of selection in
malignant populations, they frequently act as members of groups where fitness of the group …

[HTML][HTML] Could the clinical target volume be omitted for radiotherapy of locally advanced non-small cell lung cancer in the modern era?

V Verma, JY Chang - Translational Lung Cancer Research, 2021 - ncbi.nlm.nih.gov
© Translational Lung Cancer Research. All rights reserved. Transl Lung Cancer Res 2021;
10 (1): 5-8| http://dx. doi. org/10.21037/tlcr-2020-19 failure in these patients are dominated …

Immunotherapy and Radiosurgery for Brain and Spine Metastases

DAR O'Brien, H Vulpe, TJC Wang - Image-Guided …, 2021 - taylorfrancis.com
Brain metastases (BrM) are a significant cause of morbidity and mortality, occurring in
approximately 10% to 30% of cancer patients at one point in the course of their disease. In …

[引用][C] Oligometastatic disease in context of the radiation oncology alternative payment model: Implications for local consolidative therapy

MS Ning, D Boyce-Fappiano, NG Thaker - JCO Oncology Practice, 2021 - ascopubs.org
Local consolidative therapy (LCT) has emerged as a novel paradigm for the oligometastatic
patient population, 1 which is estimated to grow by nearly 2% each year. 2 Associated …