MCP-1: Function, regulation, and involvement in disease

S Singh, D Anshita, V Ravichandiran - International immunopharmacology, 2021 - Elsevier
Abstract MCP-1 (Monocyte chemoattractant protein-1), also known as Chemokine (CC-motif)
ligand 2 (CCL2), is from family of CC chemokines. It has a vital role in the process of …

Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention

X Zhu, Z Chen, W Shen, G Huang, JM Sedivy… - Signal transduction and …, 2021 - nature.com
Remarkable progress in ageing research has been achieved over the past decades.
General perceptions and experimental evidence pinpoint that the decline of physical …

Immunomodulatory effects of dietary polyphenols

H Shakoor, J Feehan, V Apostolopoulos, C Platat… - Nutrients, 2021 - mdpi.com
Functional and nutraceutical foods provide an alternative way to improve immune function to
aid in the management of various diseases. Traditionally, many medicinal products have …

Macrophage plasticity and atherosclerosis therapy

P Lin, HH Ji, YJ Li, SD Guo - Frontiers in molecular biosciences, 2021 - frontiersin.org
Atherosclerosis is a chronic disease starting with the entry of monocytes into the
subendothelium and the subsequent differentiation into macrophages. Macrophages are the …

The JAK–STAT pathway: an emerging target for cardiovascular disease in rheumatoid arthritis and myeloproliferative neoplasms

C Baldini, FR Moriconi, S Galimberti… - European Heart …, 2021 - academic.oup.com
Inflammation contributes centrally to cardiovascular diseases, and anti-inflammatory
treatments can reduce cardiovascular events. The JAK–STAT pathway is an emerging target …

Anti-inflammatory therapy for atherosclerosis: focusing on cytokines

AV Poznyak, D Bharadwaj, G Prasad… - International journal of …, 2021 - mdpi.com
Atherosclerosis is a well-known global health problem. Despite the high prevalence of the
disease, numerous aspects of pathogenesis remain unclear. Subsequently, there are still no …

3D printing advances in the development of stents

R Khalaj, AG Tabriz, MI Okereke… - International journal of …, 2021 - Elsevier
Abstract 3D printing technologies have found several applications within the biomedical
sector including in the fabrication of medical devices, advanced visualization, diagnosis …

Time-restricted eating to improve cardiovascular health

K Gabel, S Cienfuegos, F Kalam, M Ezpeleta… - Current atherosclerosis …, 2021 - Springer
Abstract Purpose of Review Time-restricted eating (TRE) is a form of intermittent fasting that
involves confining the eating window to 4–10 h and fasting for the remaining hours of the …

Immunomodulatory nanosystems for treating inflammatory diseases

N Ahamad, A Kar, S Mehta, M Dewani, V Ravichandran… - Biomaterials, 2021 - Elsevier
Inflammatory disease (ID) is an umbrella term encompassing all illnesses involving chronic
inflammation as the central manifestation of pathogenesis. These include, inflammatory …

The entry and egress of monocytes in atherosclerosis: a biochemical and biomechanical driven process

H Kang, X Li, K Xiong, Z Song, J Tian… - Cardiovascular …, 2021 - Wiley Online Library
In accordance with “the response to injury” theory, the entry of monocytes into the intima
guided by inflammation signals, taking up cholesterol and transforming into foam cells, and …