Luteolin alleviates non-alcoholic fatty liver disease in rats via restoration of intestinal mucosal barrier damage and microbiota imbalance involving in gut-liver axis

X Liu, R Sun, Z Li, R Xiao, P Lv, X Sun… - Archives of biochemistry …, 2021 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is demonstrated to be closely related to the
disorder of gut microbiota and the intestinal mucosal barrier. Luteolin is a natural flavonoid …

Efficacy and safety of traditional Chinese medicines for non-alcoholic fatty liver disease: a systematic literature review of randomized controlled trials

Z Liang, X Chen, J Shi, H Hu, Y Xue, COL Ung - Chinese medicine, 2021 - Springer
Background Non-alcoholic fatty liver disease (NAFLD) is a common liver disease that may
progress into, in the absence of proper treatment, severe liver damage. While the optimal …

Gastrodin improves nonalcoholic fatty liver disease through activation of the adenosine monophosphate–activated protein kinase signaling pathway

J Wan, Y Zhang, D Yang, Y Liang, L Yang, S Hu… - …, 2021 - Wiley Online Library
Background and Aims NASH is currently one of the most common causes of liver
transplantation and hepatocellular carcinoma. Thus far, there is still no effective …

[PDF][PDF] Modeling PNPLA3‐Associated NAFLD Using Human‐Induced Pluripotent Stem Cells

SG Tilson, CM Morell, AS Lenaerts, SB Park, Z Hu… - …, 2021 - Wiley Online Library
Background and Aims NAFLD is a growing public health burden. However, the
pathogenesis of NAFLD has not yet been fully elucidated, and the importance of genetic …

[HTML][HTML] Bupleuri radix extract ameliorates impaired lipid metabolism in high-fat diet-induced obese mice via gut microbia-mediated regulation of FGF21 signaling …

L Wu, Q Yan, F Chen, C Cao, S Wang - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Background Obesity and its comorbidities are associated with abnormal lipid metabolism
and gut microbiota dysbiosis. Bupleuri Radix is a medicinal plant used in traditional Chinese …

Ethanol Extract of Liriope platyphylla Root Attenuates Non-Alcoholic Fatty Liver Disease in High-Fat Diet-Induced Obese Mice via Regulation of Lipogenesis and …

TNH Le, HJ Choi, HS Jun - Nutrients, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a common metabolic disorder that causes
excess lipid accumulation in the liver and is the leading cause of end-stage liver disease …

Hepatoprotective effect of Qushihuayu formula on non-alcoholic steatohepatitis induced by MCD diet in rat

Q Lan, Z Ren, Y Chen, G Cui, IC Choi, COL Ung… - Chinese Medicine, 2021 - Springer
Background Non-alcoholic steatohepatitis (NASH) is an advanced form of non-alcoholic fatty
liver disease (NAFLD) for which there is yet any standard pharmacotherapy. Traditional …

[PDF][PDF] Protective effect of saikosaponin-d on H2O2-induced hepatocellular injury and its mechanism

XF Huang, ZG Liu, P Lei, ZJ Meng… - 中国药理学与毒 …, 2021 - cjpt.magtechjournal.com
OBJECTIVE To investigate the effects of saikosaponin-d (SSd) on the proliferation of L02
cells induced by H 2 O 2 and the mechanism. METHODS ① L02 cells were pretreated with …

Mechanism of Natural Drugs on Nonalcoholic Fatty Liver Disease

J Xie, L Li, L Zhao - Mini Reviews in Medicinal Chemistry, 2021 - ingentaconnect.com
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the
world. Its pathogenesis is closely related to insulin resistance, obesity, type 2 diabetes, and …

[HTML][HTML] Chinese medicine formulas for nonalcoholic fatty liver disease: Overview of systematic reviews

L Dai, WJ Zhou, LLD Zhong, XD Tang… - World Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Nonalcoholic fatty liver disease (NAFLD) affects more than one-quarter of
the global population. Due to the lack of approved chemical agents, many patients seek …