The biology and rationale of targeting nectin-4 in urothelial carcinoma

EI Heath, JE Rosenberg - Nature Reviews Urology, 2021 - nature.com
Bladder cancer is the tenth most common cancer type worldwide. Urothelial carcinoma is the
most common type of bladder cancer and accounts for 90% of bladder cancer cases in the …

MRI and CT bladder segmentation from classical to deep learning based approaches: Current limitations and lessons

MG Bandyk, DR Gopireddy, C Lall, KC Balaji… - Computers in Biology …, 2021 - Elsevier
Precise determination and assessment of bladder cancer (BC) extent of muscle invasion
involvement guides proper risk stratification and personalized therapy selection. In this …

[HTML][HTML] Quality of life after bladder cancer: a cross-sectional survey of patient-reported outcomes

JWF Catto, A Downing, S Mason, P Wright, K Absolom… - European urology, 2021 - Elsevier
Background Little is known about health-related quality of life (HRQOL) following treatment
for bladder cancer (BC). Objective To determine this, we undertook a cross-sectional survey …

[HTML][HTML] Development of prognostic signature based on immune-related genes in muscle-invasive bladder cancer: bioinformatics analysis of TCGA database

K Jin, S Qiu, D Jin, X Zhou, X Zheng, J Li, X Liao… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Background: Muscle-invasive bladder cancer (MIBC) with high tumor stages accounts for
most bladder cancer patient mortality. Platinum-based chemotherapy provides insufficient …

Intracorporeal versus extracorporeal urinary diversion following robot-assisted radical cystectomy: a meta-analysis, cumulative analysis, and systematic review

K Tanneru, SB Jazayeri, J Kumar, MU Alam… - Journal of Robotic …, 2021 - Springer
Over the last decade, the increased utilization of robot-assisted radical cystectomy (RARC)
in the surgical treatment of muscle-invasive bladder cancer has led to an uptrend in …

Targeting major signaling pathways of bladder cancer with phytochemicals: a review

C Chestnut, D Subramaniam, P Dandawate… - Nutrition and …, 2021 - Taylor & Francis
Bladder cancer is the 9th most prevalent cancer worldwide and carries a protracted
treatment course with significant patient expense, morbidity, and mortality. Over 95% of …

Incidence and outcome of salvage cystectomy after bladder sparing therapy for muscle invasive bladder cancer: a systematic review and meta-analysis

VM Schuettfort, B Pradere, F Quhal, H Mostafaei… - World Journal of …, 2021 - Springer
Objective We conducted a systematic review and meta-analysis to assess the available
literature regarding the surgical and oncologic outcomes of patients undergoing salvage …

Current status and future perspectives of immunotherapy in bladder cancer treatment

Z Wu, J Liu, R Dai, S Wu - Science China Life Sciences, 2021 - Springer
The treatment strategy of bladder cancer has evolved not only through the traditional
modalities of surgery and chemotherapy but also by immunotherapy over the past several …

The ECM modulator ITIH5 affects cell adhesion, motility and chemotherapeutic response of basal/squamous-like (BASQ) bladder cancer cells

M Rose, E Noetzel, J Kistermann, J Eschenbruch… - Cells, 2021 - mdpi.com
This study aims at characterizing the role of the putative tumor suppressor ITIH5 in basal-
type bladder cancers (BLCA). By sub-classifying TCGA BLCA data, we revealed …

Cytotoxic and chemosensitizing effects of glycoalkaloidic extract on 2D and 3D models using RT4 and patient derived xenografts bladder cancer cells

MA Miranda, PD Marcato, A Mondal… - Materials Science and …, 2021 - Elsevier
Glycoalkaloids have been widely demonstrated as potential anticancer agents. However,
the chemosensitizing effect of these compounds with traditional chemotherapeutic agents …