Cytokines as therapeutic targets for cardio-and cerebrovascular diseases
Despite major advances in prevention and treatment, cardiac and cerebral atherothrombotic
complications still account for substantial morbidity and mortality worldwide. In this context …
complications still account for substantial morbidity and mortality worldwide. In this context …
Revisiting astrocytic roles in methylmercury intoxication
GP Arrifano, M Augusto-Oliveira… - Molecular …, 2021 - Springer
Intoxication by heavy metals such as methylmercury (MeHg) is recognized as a global
health problem, with strong implications in central nervous system pathologies. Most of …
health problem, with strong implications in central nervous system pathologies. Most of …
Selective interleukin-6 trans-signaling blockade is more effective than panantagonism in reperfused myocardial infarction
MJ George, NH Jasmin, VT Cummings… - Basic to Translational …, 2021 - jacc.org
Summary Interleukin (IL)-6 is an emerging therapeutic target in myocardial infarction (MI). IL-
6 has 2 distinct signaling pathways: trans-signaling, which mediates inflammation, and …
6 has 2 distinct signaling pathways: trans-signaling, which mediates inflammation, and …
The RNase MCPIP3 promotes skin inflammation by orchestrating myeloid cytokine response
CCCH zinc finger proteins resolve immune responses by degrading the mRNAs of
inflammatory cytokines such as tumor necrosis factor (TNF) and interleukin (IL)-6. Here we …
inflammatory cytokines such as tumor necrosis factor (TNF) and interleukin (IL)-6. Here we …
Effects of spinal manipulative therapy on inflammatory mediators in patients with non-specific low back pain: a non-randomized controlled clinical trial
JA Teodorczyk-Injeyan, JJ Triano, R Gringmuth… - Chiropractic & manual …, 2021 - Springer
Background The inflammatory profiles of patients with acute and chronic nonspecific low
back pain (LBP) patients are distinct. Spinal manipulative therapy (SMT) has been shown to …
back pain (LBP) patients are distinct. Spinal manipulative therapy (SMT) has been shown to …
Effect of inflammatory cytokines/chemokines on pulmonary tuberculosis culture conversion and disease severity in HIV-infected and-uninfected individuals from South …
S Rambaran, K Naidoo, L Lewis… - Frontiers in …, 2021 - frontiersin.org
Novel tuberculosis (TB) prevention and control strategies are urgently required. Utilising
specimens from the Improving Retreatment Success (NCT02114684) trial we assessed the …
specimens from the Improving Retreatment Success (NCT02114684) trial we assessed the …
Pharmacological treatment to reduce pulmonary morbidity after esophagectomy
H Shinozaki, T Matsuoka… - Annals of …, 2021 - Wiley Online Library
Esophagectomy for esophageal cancer is one of the most invasive procedures in
gastrointestinal surgery. An invasive surgical procedure causes postoperative lung injury …
gastrointestinal surgery. An invasive surgical procedure causes postoperative lung injury …
Baseline Values and Kinetics of IL‐6, Procalcitonin, and TNF‐α in Landrace‐Large White Swine Anesthetized with Propofol‐Based Total Intravenous Anesthesia
A Chalkias, V Spyropoulos, G Georgiou… - BioMed Research …, 2021 - Wiley Online Library
The baseline levels of various inflammatory mediators and their changes during anesthesia
in swine are not known. The aim of this animal study was to measure the baseline values …
in swine are not known. The aim of this animal study was to measure the baseline values …
Targeting cytokines and immune checkpoints in atherosclerosis with monoclonal antibodies
Over the past fifteen years, treatments using monoclonal antibodies specifically targeting
cytokines have been developed to treat chronic inflammatory diseases, including …
cytokines have been developed to treat chronic inflammatory diseases, including …