Troponin variants as markers of skeletal muscle health and diseases

M Rasmussen, JP Jin - Frontiers in physiology, 2021 - frontiersin.org
Ca2+-regulated contractility is a key determinant of the quality of muscles. The sarcomeric
myofilament proteins are essential players in the contraction of striated muscles. The …

Age-related skeletal muscle dysfunction is aggravated by obesity: an investigation of contractile function, implications and treatment

J Tallis, S Shelley, H Degens, C Hill - Biomolecules, 2021 - mdpi.com
Obesity is a global epidemic and coupled with the unprecedented growth of the world's older
adult population, a growing number of individuals are both old and obese. Whilst both …

The effects of diet composition and chronic obesity on muscle growth and function

LGO de Sousa, AG Marshall… - Journal of Applied …, 2021 - journals.physiology.org
Diet-induced obesity (DIO) is associated with glucose intolerance, insulin resistance (IR),
and an increase in intramyocellular lipids (IMCL), which may lead to disturbances in glucose …

Current perspectives on obesity and skeletal muscle contractile function in older adults

CR Straight, MJ Toth, MS Miller - Journal of Applied …, 2021 - journals.physiology.org
Obesity has become one of the most pressing public health issues of the 21st century and
currently affects a substantial proportion of the older adult population. Although the …

Influence of obesity and type 2 diabetes on calcium handling by skeletal muscle: spotlight on the sarcoplasmic reticulum and mitochondria

H Eshima - Frontiers in Physiology, 2021 - frontiersin.org
Obesity and diabetes have been shown to interfere with energy metabolism and cause
peripheral insulin resistance in skeletal muscle. However, recent studies have focused on …

Maintenance of contractile force and increased fatigue resistance in slow-twitch skeletal muscle of mice fed a high-fat diet

H Eshima, Y Tamura, S Kakehi… - Journal of Applied …, 2021 - journals.physiology.org
Consumption of a high-fat diet (HFD) significantly increases exercise endurance
performance during treadmill running. However, whether HFD consumption increases …

Physiological and pathophysiological concentrations of fatty acids induce lipid droplet accumulation and impair functional performance of tissue engineered skeletal …

MC Turner, RP Rimington, NRW Martin… - Journal of Cellular …, 2021 - Wiley Online Library
Fatty acids (FA) exert physiological and pathophysiological effects leading to changes in
skeletal muscle metabolism and function, however, in vitro models to investigate these …

Contractility of permeabilized rat vastus intermedius muscle fibres following high-fat, high-sucrose diet consumption

IC Smith, C Ostertag, JJ O'reilly, JL Rios… - Applied Physiology …, 2021 - cdnsciencepub.com
Obesity is a worldwide health concern associated with impaired physical function. It is not
clear if contractile protein dysfunction contributes to the impairment of muscle function …

The effects of high adiposity on concentric and eccentric muscle performance of upper and lower limb musculature in young and older adults

S Shelley, RS James, S Eustace… - Applied Physiology …, 2021 - cdnsciencepub.com
The present study uniquely examined the influence of old age and adiposity on maximal
concentric and eccentric torque and fatigue of the elbow and knee (KF, KE) flexors and …

Vliv pohybové intervence na muskuloskeletální systém u pacientů před a po plánované bariatrické operaci

N Cibulková - 2021 - dspace.cuni.cz
Název: Vliv pohybové intervence na muskuloskeletální systém u pacientů před a po
plánované bariatrické operaci. Cíle: Hlavním cílem této studie bylo zhodnotit vliv tříměsíční …