Regulation of Nuclear Factor-KappaB (NF-κB) signaling pathway by non-coding RNAs in cancer: Inhibiting or promoting carcinogenesis?

S Mirzaei, A Zarrabi, F Hashemi, A Zabolian, H Saleki… - Cancer Letters, 2021 - Elsevier
The nuclear factor-kappaB (NF-κB) signaling pathway is considered as a potential
therapeutic target in cancer therapy. It has been well established that transcription factor NF …

[HTML][HTML] Coumarins and gastrointestinal cancer: a new therapeutic option?

Z Banikazemi, SM Mirazimi, F Dashti… - Frontiers in …, 2021 - frontiersin.org
Cancers of the gastrointestinal (GI) tract are often life-threatening malignancies, which can
be a severe burden to the health care system. Globally, the mortality rate from …

[HTML][HTML] 3-Formylchromone counteracts STAT3 signaling pathway by elevating SHP-2 expression in hepatocellular carcinoma

CD Mohan, MH Yang, S Rangappa, A Chinnathambi… - Biology, 2021 - mdpi.com
Simple Summary STAT3 acts as a potential tumor-promoting transcription factor that gets
aberrantly activated in several types of human cancers and plays a crucial role in tumor …

Cytochrome P450 1A2 overcomes nuclear factor kappa B-mediated sorafenib resistance in hepatocellular carcinoma

J Yu, N Wang, Z Gong, L Liu, S Yang, GG Chen… - Oncogene, 2021 - nature.com
Sorafenib resistance has become the main obstacle in the effective treatment of advanced
hepatocellular carcinoma (HCC) patients. Activation of nuclear factor kappa B (NF‐κB) is a …

[HTML][HTML] Autophagy promotes cigarette smoke-initiated and elastin-driven bronchitis-like airway inflammation in mice

HQ Huang, N Li, DY Li, D Jing, ZY Liu, XC Xu… - Frontiers in …, 2021 - frontiersin.org
Cigarette smoke (CS)-induced macrophage activation and airway epithelial injury are both
critical for the development of chronic obstructive pulmonary disease (COPD), while the …

Preliminary investigation of the chemo diversity of bioactive molecules produced by endophytic fungi isolated from Manihot utilisima leaf

UM Okezie, PM Eze, FBC Okoye… - GSC Biological and …, 2021 - gsconlinepress.com
Endophytic fungi have demonstrated a harmless relationship living within the internal
tissues of several plant hosts and at the same time produce diverse important bioactive …

Molecular Docking studies of 3-substituted 4-phenylamino coumarin derivatives as Chemokine receptor inhibitor

S Debasish, S Tripti - Research Journal of Pharmacy and …, 2021 - indianjournals.com
Chemokines are small chemotactic cytokines, which play a significant role in the control of
cell migration during immune surveillance and inflammation. Chemokines are responsible …