[HTML][HTML] Stimuli-responsive transdermal microneedle patches

P Makvandi, R Jamaledin, G Chen… - Materials Today, 2021 - Elsevier
Microneedle (MN) patches consisting of miniature needles have emerged as a promising
tool to perforate the stratum corneum and translocate biomolecules into the dermis in a …

Microneedles in drug delivery: progress and challenges

M Avcil, A Çelik - Micromachines, 2021 - mdpi.com
In recent years, an innovative transdermal delivery technology has attracted great interest for
its ability to distribute therapeutics and cosmeceuticals for several applications, including …

Advances of microneedles in biomedical applications

J Xu, D Xu, X Xuan, H He - Molecules, 2021 - mdpi.com
A microneedle (MN) is a painless and minimally invasive drug delivery device initially
developed in 1976. As microneedle technology evolves, microneedles with different shapes …

Translation of polymeric microneedles for treatment of human diseases: Recent trends, Progress, and Challenges

PR Yadav, MN Munni, L Campbell, G Mostofa… - Pharmaceutics, 2021 - mdpi.com
The ongoing search for biodegradable and biocompatible microneedles (MNs) that are
strong enough to penetrate skin barriers, easy to prepare, and can be translated for clinical …

Recent advances on microneedle arrays-mediated technology in cancer diagnosis and therapy

V Alimardani, SS Abolmaali, AM Tamaddon… - Drug Delivery and …, 2021 - Springer
Regarding the increasing prevalence of cancer throughout the globe, the development of
novel alternatives for conventional therapies is inevitable to circumvent limitations such as …

[HTML][HTML] Recent advances in microneedles-mediated transdermal delivery of protein and peptide drugs

T Liu, M Chen, J Fu, Y Sun, C Lu, G Quan, X Pan… - … Pharmaceutica Sinica B, 2021 - Elsevier
Proteins and peptides have become a significant therapeutic modality for various diseases
because of their high potency and specificity. However, the inherent properties of these …

Recent advances on fabrication of microneedles on the flexible substrate

D Huang, J Li, T Li, Z Wang, Q Wang… - … of Micromechanics and …, 2021 - iopscience.iop.org
Microneedles are able to penetrate into the skin and offer great chances in various
biomedical applications including transdermal drug delivery, stable bio-signal monitoring …

Layer-by-layer fabrication of hydrogel microsystems for controlled drug delivery from untethered microrobots

R Bernasconi, F Pizzetti, A Rossetti, B Butler… - … in Bioengineering and …, 2021 - frontiersin.org
Targeted drug delivery from untethered microrobots is a topic of major interest in current
biomedical research. The possibility to load smart materials able to administer active …

Transmitting light through biocompatible and biodegradable drug delivery micro needles

S Coppola, V Vespini, G Nasti… - IEEE Journal of Selected …, 2021 - ieeexplore.ieee.org
The use of micro-needle for advanced self-administration and cutaneous therapy still
represent a desired solution that could open towards still unexplored medical market …

Transient modelling of impact driven needle-free injectors

YS Rane, JO Marston - Computers in biology and medicine, 2021 - Elsevier
Needle-free jet injectors (NFJIs) are one of the alternatives to hypodermic needles for
transdermal drug delivery. These devices use a high-velocity jet stream to puncture the skin …