[HTML][HTML] Requirements of postnatal proBDNF in the hippocampus for spatial memory consolidation and neural function

W Sun, H Cheng, Y Yang, D Tang, X Li… - Frontiers in Cell and …, 2021 - frontiersin.org
Mature brain-derived neurotrophic factor (BDNF) and its downstream signaling pathways
have been implicated in regulating postnatal development and functioning of rodent brain …

Light promotes neural correlates of fear memory via enhancing brain-derived neurotrophic factor (BDNF) expression in the prelimbic cortex

W Sun, Y Yang, X Chen, Y Cheng, X Li… - ACS Chemical …, 2021 - ACS Publications
Exposure to light has been shown to enhance vigilance and improve working memory,
possibly due to changes in prefrontal function. Ample evidence supports the critical role of …

Functional expression of TrkB receptors on interneurones and pyramidal cells of area CA3 of the rat hippocampus

E Griego, G Herrera-López, G Gómez-Lira… - …, 2021 - Elsevier
The dentate gyrus and hippocampal area CA3 region of the mammalian brain contains the
highest levels of brain-derived neurotrophic factor (BDNF) and its canonical membrane …

ProBDNF induces sustained elevation of intracellular Ca2+ possibly mediated by TRPM7 channels in rodent microglial cells

Y Mizoguchi, M Ohgidani, Y Haraguchi… - Glia, 2021 - Wiley Online Library
Microglia are intrinsic immune cells that release factors including pro‐and anti‐inflammatory
cytokines, nitric oxide (NO) and neurotrophins following activation in the brain. Elevation of …

The involvement of ADAR1 in antidepressant action by regulating BDNF via miR-432

X Zhang, Y Xue, J Li, H Xu, W Yan, Z Zhao, W Yu… - Behavioural Brain …, 2021 - Elsevier
Brain-derived neurotrophic factor (BDNF) is a biomarker of depression. Recent studies have
found adenosine deaminase acting on RNA1 (ADAR1) is a novel target being sensitive to …

A TrkB antibody agonist promotes plasticity after cervical spinal cord injury in adult rats

K Fouad, R Vavrek, S Cho - Journal of neurotrauma, 2021 - liebertpub.com
After spinal cord injury (SCI) in mammals, there is only limited repair and, consequently, only
moderate recovery. One mechanism frequently discussed to be involved in this recovery is …

Early induction of neurotrophin receptor and miRNA genes in mouse brain after pentilenetetrazole-induced neuronal activity

AA Shmakova, KD Rysenkova, OI Ivashkina… - Biochemistry …, 2021 - Springer
Neurotrophin receptors regulate neuronal survival and network formation, as well as
synaptic plasticity in the brain via interaction with their ligands. Here, we examined early …

[PDF][PDF] Trapped in the net: restriction of TRKB function by perineuronal nets inhibits plasticity in the central nervous system

A Lesnikova - 2021 - helda.helsinki.fi
Induction of neuronal plasticity by drugs and physiological mechanisms has been an
important topic in the modern neuroscience investigations due to its potential to restore …

РАННЯЯ ИНДУКЦИЯ ГЕНОВ РЕЦЕПТОРОВ НЕЙРОТРОФИНОВ И микроРНК В ГОЛОВНОМ МОЗГЕ МЫШЕЙ ПОСЛЕ ПЕНТИЛЕНТЕТРАЗОЛ …

АА Шмакова, КД Рысенкова, ОИ Ивашкина… - Биохимия, 2021 - elibrary.ru
Рецепторы нейротрофинов, взаимодействуя со своими лигандами, регулируют в
головном мозге выживаемость нервных клеток, формирование нейронных связей и …