Ankylosing spondylitis: an autoimmune or autoinflammatory disease?

D Mauro, R Thomas, G Guggino, R Lories… - Nature Reviews …, 2021 - nature.com
Ankylosing spondylitis (AS) is a chronic inflammatory disorder of unknown aetiology. Unlike
other systemic autoimmune diseases, in AS, the innate immune system has a dominant role …

[HTML][HTML] Pathogenesis and function of interleukin-35 in rheumatoid arthritis

PL Xin, LF Jie, Q Cheng, DY Bin… - Frontiers in Pharmacology, 2021 - frontiersin.org
It is well known that RA (Rheumatoid arthritis) is an autoimmune disease characterized by
multiple and symmetric arthropathy. The main pathological features of RA are synovial …

[HTML][HTML] Eubacterium rectale Attenuates HSV-1 Induced Systemic Inflammation in Mice by Inhibiting CD83

SMS Islam, HM Ryu, HM Sayeed, HO Byun… - Frontiers in …, 2021 - frontiersin.org
The purpose of this study was to determine whether administration of the microorganism
Eubacterium rectale (E. rectale) could regulate dendritic cell (DC) activation and systemic …

Role of intestinal microbiota on gut homeostasis and rheumatoid arthritis

M Li, F Wang - Journal of immunology research, 2021 - Wiley Online Library
Rheumatoid arthritis (RA) is a chronic inflammatory disease that is immune mediated.
Patients typically present with synovial inflammation, which gradually deteriorates to …

Recent updates in the immunopathology of type 3 immunity-mediated enthesitis

A Nakamura, N Haroon - Current Rheumatology Reports, 2021 - Springer
Abstract Purpose of Review Enthesitis is a cardinal feature of spondyloarthritis (SpA).
Despite increasing available treatments, challenges remain in adequately controlling …

Contribution of mycobiota to the pathogenesis of spondyloarthritis

JM Berthelot, C Darrieutort-Laffite, C Trang, Y Maugars… - Joint Bone Spine, 2021 - Elsevier
This review lists current evidences for a contribution of gut mycobiota to the pathogenesis of
SpA and related conditions. Gut mycobiota has a small size as compared to bacterial …

Crossing the boundaries: IL-23 and its role in linking inflammation of the skin, gut and joints

Z Łukasik, E Gracey, K Venken, C Ritchlin… - …, 2021 - academic.oup.com
Several lines of evidence point towards the central role of IL-23 as a crucial inflammatory
mediator in the pathogenesis of SpA—a group of inflammatory arthritic diseases whose …

[HTML][HTML] Haptoglobin and its related protein, zonulin—what is their role in spondyloarthropathy?

M Chmielińska, M Olesińska… - Journal of Clinical …, 2021 - mdpi.com
Haptoglobin (Hp) is an acute phase protein which supports the immune response and
protects tissues from free radicals. Its concentration correlates with disease activity in …

Effect of Duyun Compound Green Tea on Gut Microbiota Diversity in High‐Fat‐Diet‐Induced Mice Revealed by Illumina High‐Throughput Sequencing

C Zhou, X Zhou, Z Wen, Z Yang, R Mu… - Evidence‐Based …, 2021 - Wiley Online Library
Intake of a high‐fat diet (HFD) is closely related to disorders of the intestinal microbiota,
which plays a key role in the pathogenesis of obesity. Duyun compound green tea, an …

[PDF][PDF] IMIDs

DX Xibillé-Friedmann - Rev Mex Enferm Inflam Inmunomed, 2021 - researchgate.net
The human organism maintains a symbiotic relationship with a great variety of bacterial, viral
and fungal microorganisms, the whole of which is called the microbiota. The microbiota and …