Cardiac fibrosis
NG Frangogiannis - Cardiovascular research, 2021 - academic.oup.com
Myocardial fibrosis, the expansion of the cardiac interstitium through deposition of
extracellular matrix proteins, is a common pathophysiologic companion of many different …
extracellular matrix proteins, is a common pathophysiologic companion of many different …
COVID-19 myocarditis and prospective heart failure burden
Introduction: COVID-19 is causing considerable morbidity and mortality worldwide. Serious
respiratory complications aside, the heart is also frequently involved. The mechanisms and …
respiratory complications aside, the heart is also frequently involved. The mechanisms and …
Empagliflozin ameliorates diastolic dysfunction and left ventricular fibrosis/stiffness in nondiabetic heart failure: a multimodality study
CG Santos-Gallego, JA Requena-Ibanez… - Cardiovascular …, 2021 - jacc.org
Objectives The purpose of this study was to investigate the effect of empagliflozin on
diastolic function in a nondiabetic heart failure with reduced ejection fraction (HFrEF) …
diastolic function in a nondiabetic heart failure with reduced ejection fraction (HFrEF) …
Effect of neprilysin inhibition on left ventricular remodeling in patients with asymptomatic left ventricular systolic dysfunction late after myocardial infarction
KF Docherty, RT Campbell, KJM Brooksbank… - Circulation, 2021 - Am Heart Assoc
Background: Patients with left ventricular (LV) systolic dysfunction after myocardial infarction
are at a high risk of developing heart failure. The addition of neprilysin inhibition to renin …
are at a high risk of developing heart failure. The addition of neprilysin inhibition to renin …
Prognostic value of myocardial extracellular volume fraction evaluation based on cardiac magnetic resonance T1 mapping with T1 long and short in hypertrophic …
Y Li, X Liu, F Yang, J Wang, Y Xu, TT Fang, LT Pu… - European …, 2021 - Springer
Objective To investigate the prognostic significance of T1 mapping using T1 long and short
in hypertrophic cardiomyopathy (HCM) patients. Methods A total of 263 consecutive patients …
in hypertrophic cardiomyopathy (HCM) patients. Methods A total of 263 consecutive patients …
[HTML][HTML] Myocardial T1-mapping and extracellular volume in pulmonary arterial hypertension: A systematic review and meta-analysis
Introduction Elevated myocardial T 1-mapping and extracellular volume (ECV) measured on
cardiac MR (CMR) imaging is associated with myocardial abnormalities such as oedema or …
cardiac MR (CMR) imaging is associated with myocardial abnormalities such as oedema or …
Cardiovascular outcomes in systemic sclerosis with abnormal cardiovascular MRI and serum cardiac biomarkers
RB Dumitru, LA Bissell, B Erhayiem, A Kidambi… - RMD open, 2021 - rmdopen.bmj.com
Objectives To explore the prognostic value of subclinical cardiovascular (CV) imaging
measures and serum cardiac biomarkers in systemic sclerosis (SSc) for the development of …
measures and serum cardiac biomarkers in systemic sclerosis (SSc) for the development of …
Predictors of subclinical systemic sclerosis primary heart involvement characterised by microvasculopathy and myocardial fibrosis
RB Dumitru, LA Bissell, B Erhayiem, G Fent… - …, 2021 - academic.oup.com
Objectives SSc primary heart involvement (SSc-pHI) is a significant cause of mortality. We
aimed to characterize and identify predictors of subclinical SSc-pHI using cardiovascular …
aimed to characterize and identify predictors of subclinical SSc-pHI using cardiovascular …
Collagen‐Targeted Peptides for Molecular Imaging of Diffuse Cardiac Fibrosis
Background Cardiac fibrosis is the excessive deposition of extracellular matrix in the heart,
triggered by a cardiac insult, aging, genetics, or environmental factors. Molecular imaging of …
triggered by a cardiac insult, aging, genetics, or environmental factors. Molecular imaging of …
[HTML][HTML] The association of reduced left ventricular strains with increased extracellular volume and their collective impact on clinical outcomes
Background Myocardial fibrosis and left ventricular (LV) longitudinal strain are
independently associated with adverse clinical outcomes. However, the relationship …
independently associated with adverse clinical outcomes. However, the relationship …