COVID-19 vaccine: A recent update in pipeline vaccines, their design and development strategies

K Rawat, P Kumari, L Saha - European journal of pharmacology, 2021 - Elsevier
Coronavirus Disease 2019 named as COVID-19 imposing a huge burden on public health
as well as global economies, is caused by a new strain of betacoronavirus named as SARS …

Bacterial outer membrane vesicles as a versatile tool in vaccine research and the fight against antimicrobial resistance

Z Zhu, F Antenucci, KR Villumsen, AM Bojesen - MBio, 2021 - Am Soc Microbiol
Gram-negative bacteria include a number of pathogens that cause disease in humans and
animals. Although antibiotics are still effective in treating a considerable range of infections …

Designing of a multi-epitope vaccine against the structural proteins of marburg virus exploiting the immunoinformatics approach

SA Sami, KKS Marma, S Mahmud, MAN Khan… - ACS …, 2021 - ACS Publications
Marburg virus disease (MVD) caused by the Marburg virus (MARV) generally appears with
flu-like symptoms and leads to severe hemorrhagic fever. It spreads via direct contact with …

Vaccinology in the post− COVID-19 era

R Rappuoli, E De Gregorio… - Proceedings of the …, 2021 - National Acad Sciences
The COVID-19 pandemic is a shocking reminder of how our world would look in the
absence of vaccination. Fortunately, new technologies, the pace of understanding new and …

Deep learning techniques and COVID-19 drug discovery: Fundamentals, state-of-the-art and future directions

MB Jamshidi, A Lalbakhsh, J Talla, Z Peroutka… - … Technologies During the …, 2021 - Springer
The world is in a frustrating situation, which is exacerbating due to the time-consuming
process of the COVID-19 vaccine design and production. This chapter provides a …

The relevance of bioinformatics applications in the discovery of vaccine candidates and potential drugs for COVID-19 treatment

OS Chukwudozie, VC Duru… - … and Biology Insights, 2021 - journals.sagepub.com
The application of bioinformatics to vaccine research and drug discovery has never been so
essential in the fight against infectious diseases. The greatest combat of the 21st century …

Current and prospective computational approaches and challenges for developing COVID-19 vaccines

W Hwang, W Lei, NM Katritsis, M MacMahon… - Advanced drug delivery …, 2021 - Elsevier
Abstract SARS-CoV-2, which causes COVID-19, was first identified in humans in late 2019
and is a coronavirus which is zoonotic in origin. As it spread around the world there has …

Structure‐guided envelope trimer design in HIV‐1 vaccine development: a narrative review

R Derking, RW Sanders - Journal of the International AIDS …, 2021 - Wiley Online Library
Introduction The development of a human immunodeficiency virus 1 (HIV‐1) vaccine
remains a formidable challenge. An effective vaccine likely requires the induction of broadly …

[HTML][HTML] Design of a multi-epitope vaccine against cervical cancer using immunoinformatics approaches

S Sanami, F Azadegan-Dehkordi… - Scientific Reports, 2021 - nature.com
Cervical cancer, caused by human papillomavirus (HPV), is the fourth most common type of
cancer among women worldwide. While HPV prophylactic vaccines are available, they have …

A conceptual deep learning framework for COVID-19 drug discovery

MB Jamshidi, J Talla, A Lalbakhsh… - 2021 IEEE 12th …, 2021 - ieeexplore.ieee.org
The analytical and experimental methods used for the development of drugs have some
disadvantages in the aspect of the needed time for preparation of the desired …