Wnt-frizzled signaling regulates activity-mediated synapse formation
S Teo, PC Salinas - Frontiers in molecular neuroscience, 2021 - frontiersin.org
The formation of synapses is a tightly regulated process that requires the coordinated
assembly of the presynaptic and postsynaptic sides. Defects in synaptogenesis during …
assembly of the presynaptic and postsynaptic sides. Defects in synaptogenesis during …
Multiple signaling pathways are essential for synapse formation induced by synaptic adhesion molecules
X Jiang, R Sando, TC Südhof - Proceedings of the National …, 2021 - National Acad Sciences
Little is known about the cellular signals that organize synapse formation. To explore what
signaling pathways may be involved, we employed heterologous synapse formation assays …
signaling pathways may be involved, we employed heterologous synapse formation assays …
WNT signaling is a key player in Alzheimer's disease
The cellular processes regulated by WNT signaling have been mainly studied during
embryonic development and cancer. In the last two decades, the role of WNT in the adult …
embryonic development and cancer. In the last two decades, the role of WNT in the adult …
Identification of miRNA and Their Regulatory Effects Induced by Total Flavonoids From Dracocephalum moldavica in the Treatment of Vascular Dementia
M Liu, G Shan, H Jiang, L Zeng, K Zhao, Y Li… - Frontiers in …, 2021 - frontiersin.org
Vascular dementia (VaD) is a general term used to describe difficulties in memory,
reasoning, judgment, and planning caused by a reduced blood flow to the brain and …
reasoning, judgment, and planning caused by a reduced blood flow to the brain and …
Wnt5a promotes hippocampal postsynaptic development and GluN2B-induced expression via the eIF2α HRI kinase
E Ramos-Fernández, MS Arrázola, CA Oliva… - Scientific Reports, 2021 - nature.com
Wnt signaling plays a key role in neurodevelopment and neuronal maturation. Specifically,
Wnt5a stimulates postsynaptic assemblies, increases glutamatergic neurotransmission and …
Wnt5a stimulates postsynaptic assemblies, increases glutamatergic neurotransmission and …
FOXG1 directly suppresses Wnt5a during the development of the hippocampus
Y Ni, B Liu, X Wu, J Liu, R Ba, C Zhao - Neuroscience bulletin, 2021 - Springer
The Wnt signaling pathway plays key roles in various developmental processes. Wnt5a,
which activates the non-canonical pathway, has been shown to be particularly important for …
which activates the non-canonical pathway, has been shown to be particularly important for …
[HTML][HTML] In situ slow-release recombinant growth differentiation factor 11 exhibits therapeutic efficacy in ischemic stroke
HH Su, JC Yen, JM Liao, YH Wang, PH Liu… - Biomedicine & …, 2021 - Elsevier
Systemic growth differentiation factor 11 (GDF11) treatment improves the vasculature in the
hippocampus and cortex in mice in recent studies. However, systemic application of …
hippocampus and cortex in mice in recent studies. However, systemic application of …
Wnt5a modulates dendritic spine dynamics through the regulation of Cofilin via small Rho GTPase activity in hippocampal neurons
D Vallejo, CB Lindsay… - Journal of …, 2021 - Wiley Online Library
Dendritic spines are small, actin‐rich protrusions that act as the receiving sites of most
excitatory inputs in the central nervous system. The remodeling of the synapse architecture …
excitatory inputs in the central nervous system. The remodeling of the synapse architecture …
Morphological neurite changes induced by porcupine inhibition are rescued by Wnt ligands
JA Godoy, J Espinoza-Caicedo… - Cell Communication and …, 2021 - Springer
Background Wnt signaling plays key roles in cellular and physiological processes, including
cell proliferation, differentiation and migration during development and tissue homeostasis …
cell proliferation, differentiation and migration during development and tissue homeostasis …
[PDF][PDF] 丁苯酞通过调节海马突触相关蛋白表达和线粒体结构改善db/db 小鼠认知功能障碍
左旺盛， 张钰， 张玲， 秦川 - 中国比较医学杂志, 2021 - zgbjyx.cnjournals.com
丁苯酞通过调节海马突触相关蛋白表达和线粒体结构改善db/ db 小鼠认知功能障碍 Page 1 2021
年4 月 第31 卷第4 期 中国比较医学杂志 CHINESE JOURNAL OF COMPARATIVE MEDICINE …
年4 月 第31 卷第4 期 中国比较医学杂志 CHINESE JOURNAL OF COMPARATIVE MEDICINE …