The purpose of this investigation was to identify if serum interleukin (IL)-10 and tumor
necrosis factor (TNF)-α concentrations and their ratio (IL-10/TNF-α) are altered in subjects …

Inflammation plays an essential role in arthritis development and progression. Despite the
advances in the pharmaceutical field, current treatments still present low efficacy and severe …

Osteoarthritis (OA), the most common degenerative and inflammatory joint disorder, is
multifaceted. Indeed, OA characteristics include cartilage degradation, osteophytes …

Neutrophil-derived microvesicles (NDMVs) have the potential to exert anti-inflammatory
effects. Our study aimed to explore the effects of NDMVs on proinflammatory cytokines …

Osteoarthritis (OA) is a global health issue with myriad pathophysiological factors and is one
of the most common causes of chronic disability in adults due to pain and altered joint …

The serum fraction of platelet-rich fibrin (hyperacute serum) has been shown to improve
cartilage cell proliferation in in vitro osteoarthritic knee joint models. We hypothesize that …

The roles that cytokines and matrix metalloproteinases play in the onset and progression of
posttraumatic osteoarthritis (PTOA) remain a topic of debate. The study objective was to …

Objective During osteoarthritis progression, cartilage degrades in a manner that influences
its biomechanical and biotribological properties, while chondrocytes reduce the synthesis of …

Introduction: Osteoarthritis (OA) is the leading cause of pain and physical disability in the
world, in addition to being related to more than 100 rheumatological and orthopedic …

Background: Some cytokines such as IL-1β, TNF-α, VEGF, IL-6, IL-15, IL-17, IL-18, IL-4, IL-
10, and IL-13 had been found in the knee joint and demonstrated the correlation to knee …