Current understanding of the molecular and cellular pathology of diabetic retinopathy

DA Antonetti, PS Silva, AW Stitt - Nature Reviews Endocrinology, 2021 - nature.com
Diabetes mellitus has profound effects on multiple organ systems; however, the loss of
vision caused by diabetic retinopathy might be one of the most impactful in a patient's life …

Angiopoietin-like 4 promotes angiogenesis and neurogenesis in a mouse model of acute ischemic stroke

Z Qiu, J Yang, G Deng, D Li, S Zhang - Brain Research Bulletin, 2021 - Elsevier
Objective The purpose of the present study is to investigate whether angiopoietin-like 4
(ANGPTL4) can promote angiogenesis and neurogenesis following stroke, as well as to …

A NOTCH3 homozygous nonsense mutation in familial Sneddon syndrome with pediatric stroke

EK Greisenegger, S Llufriu, A Chamorro, A Cervera… - Journal of …, 2021 - Springer
Sneddon syndrome is a rare disorder affecting small and medium-sized blood vessels that is
characterized by the association of livedo reticularis and stroke. We performed whole-exome …

Circulating ANGPTL3 and ANGPTL4 levels predict coronary artery atherosclerosis severity

T Sun, W Zhan, L Wei, Z Xu, L Fan, Y Zhuo… - Lipids in Health and …, 2021 - Springer
Background We investigated the role of ANGPTL3 and ANGPTL4 in atherosclerosis
development and determined whether plasma concentrations of ANGPTL3 and ANGPTL4 …

Missense variants in hypoxia-induced VEGFA/VEGFR2 signaling predict the outcome of large artery atherosclerotic stroke

Z Li, M Wang, J Gu, L Zhao, Y Guo, Z Zhang… - Cellular and Molecular …, 2021 - Springer
Collateral density variations are a major determinant of stroke outcome. Here, we explored
the association of missense variants in hypoxia-induced VEGFA/VEGFR2 signaling and …