[HTML][HTML] Metformin-induced chemosensitization to cisplatin depends on P53 status and is inhibited by Jarid1b overexpression in non-small cell lung cancer cells

TC Tortelli Jr, RE Tamura… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Metformin has been tested as an anti-cancer therapy with potential to improve conventional
chemotherapy. However, in some cases, metformin fails to sensitize tumors to …

Exploration of p53 plus interferon-beta gene transfer for the sensitization of human colorectal cancer cell lines to cell death

PR Del Valle, SA Mendonça, F Antunes… - Cancer Biology & …, 2021 - Taylor & Francis
While treatments for colorectal cancer continue to improve, some 50% of patients succumb
within 5 years, pointing to the need for additional therapeutic options. We have developed a …

Avaliação dos efeitos autócrino e parácrino da terapia gênica com adenovírus portador de IFNbeta e sua relaçao com IFNAR1 no melanoma e microambiente murino

IL Vieira - 2021 - teses.usp.br
O câncer é uma doença complexa, frequentemente sem cura e que está presente em todas
as populações e em todas as idades. O câncer gera enormes perdas econômicas e …