Painful and non-painful diabetic neuropathy, diagnostic challenges and implications for future management

TS Jensen, P Karlsson, SS Gylfadottir, ST Andersen… - Brain, 2021 - academic.oup.com
Peripheral neuropathy is one of the most common complications of both type 1 and type 2
diabetes. Up to half of patients with diabetes develop neuropathy during the course of their …

[HTML][HTML] Hidden pharmacological activities of valproic acid: A new insight

D Singh, S Gupta, I Verma, MA Morsy, AB Nair… - Biomedicine & …, 2021 - Elsevier
Valproic acid (VPA) is an approved drug for managing epileptic seizures, bipolar disorders,
and migraine. VPA has been shown to elevate the level of gamma-aminobutyric acid …

Effect of high-frequency (10-kHz) spinal cord stimulation in patients with painful diabetic neuropathy: a randomized clinical trial

EA Petersen, TG Stauss, JA Scowcroft… - JAMA …, 2021 - jamanetwork.com
Importance Many patients with diabetic peripheral neuropathy experience chronic pain and
inadequate relief despite best available medical treatments. Objective To determine whether …

[HTML][HTML] Neuropathic pain in the elderly

S Giovannini, D Coraci, F Brau, V Galluzzo, C Loreti… - Diagnostics, 2021 - mdpi.com
Neuropathic pain due to a lesion or a disease of the somatosensory system often affects
older people presenting several comorbidities. Moreover, elderly patients are often poly …

[HTML][HTML] Diabetic neuropathy: A narrative review of risk factors, classification, screening and current pathogenic treatment options

A Bondar, AR Popa, N Papanas… - Experimental and …, 2021 - spandidos-publications.com
Diabetic neuropathy (DN) is a frequent complication of diabetes mellitus (DM) with severe
consequences as it progresses and influences all human body systems. This review …

[HTML][HTML] Neuropathic pain and rehabilitation: a systematic review of international guidelines

A Bernetti, F Agostini, A de Sire, M Mangone… - Diagnostics, 2021 - mdpi.com
Background: Neuropathic pain is an injury or disease of the central and/or peripheral
somatosensory nervous system, and it has a significant impact on quality of life, especially …

[HTML][HTML] Effect of acupuncture on diabetic neuropathy: a narrative review

E Cho, W Kim - International Journal of Molecular Sciences, 2021 - mdpi.com
Diabetic neuropathy, a major complication of diabetes mellitus, refers to a collection of
clinically diverse disorders affecting the nervous system that may present with pain …

[HTML][HTML] Electroacupuncture alleviates diabetic peripheral neuropathy by regulating glycolipid-related GLO/AGEs/RAGE axis

X Wang, Q Li, X Han, M Gong, Z Yu, B Xu - Frontiers in endocrinology, 2021 - frontiersin.org
Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes
mellitus (DM) and affects over one-third of all patients. Neuropathic pain and nerve …

[HTML][HTML] Treatment of painful diabetic neuropathy—a narrative review of pharmacological and interventional approaches

M Gupta, NN Knezevic, A Abd-Elsayed, M Ray, K Patel… - Biomedicines, 2021 - mdpi.com
Painful diabetic neuropathy (PDN) is a common complication of diabetes mellitus that is
associated with a significant decline in quality of life. Like other painful neuropathic …

Diabetic neuropathies

K Patel, H Horak, E Tiryaki - Muscle & Nerve, 2021 - Wiley Online Library
Diabetic neuropathies are the most common type of neuropathies seen in clinical practice.
These neuropathies can range clinically from asymptomatic to manifesting symptoms …