Myasthenia gravis (MG) is an autoimmune neurological disorder characterized by defective
transmission at the neuromuscular junction. The incidence of the disease is 4.1 to 30 cases …

Myasthenia gravis (MG) is an autoimmune neuromuscular disorder which is characterized
by presence of antibodies against acetylcholine receptors (AChRs) or other proteins of the …

Introduction Generalized myasthenia gravis (gMG) is an autoimmune disorder in which
pathogenic autoantibodies damage the neuromuscular junction, causing disabling or life …

Background and Objective To determine whether human anti-LRP4/agrin antibodies are
pathogenic in mice and to investigate underpinning pathogenic mechanisms. Methods …

Elevated N-linked glycosylation of IgG V regions (IgG-V N-Glyc) is an emerging molecular
phenotype associated with autoimmune disorders. To test the broader specificity of elevated …

Introduction: Myasthenia gravis (MG) is a prototypical autoimmune disease, characterized by
pathogenic autoantibodies targeting structures of the neuromuscular junction …

The incidence of neuromuscular disorders (NMDs) ranges from 0.05 to 9 per 100,000/y and
the prevalence is between 1 and 10 per 100,000 population. 1 However, they are the …

As the nervous system develops, connections between neurons must form to enable efficient
communication. This complex process of synaptic development requires the coordination of …

Introduction: Myasthenia gravis is a rare disease of the neuromuscular junction and a
prototype of B cell-driven immunopathology. Pathogenic antibodies target post-synaptic …

This study aimed to establish a cell-based assay (CBA) for the detection of agrin antibodies
(Agrin-Ab) to explore the clinical features of agrin antibody-positive Chinese patients with …