Increasing evidence suggests that mental health and physical health are linked by neural
systems that jointly regulate somatic physiology and high-level cognition. Key systems …

The subdivisions of the anterior cingulate cortex (ACC)–including subgenual, perigenual
and dorsal zones–are implicated in the etiology, pathogenesis and treatment of major …

Brain perturbation studies allow detailed causal inferences of behavioral and neural
processes. Because the combination of brain perturbation methods and neural …

Subclinical depression (dysphoria) is a common condition that may increase the risk of
major depression and leads to impaired quality of life and severe comorbid somatic …

Despite many observations of anterior cingulate cortex (ACC) activity related to cognition
and affect in humans and nonhuman animals, little is known about the causal role of the …

A crucial component of social cognition is to observe and understand the social interactions
of other individuals. A promising nonhuman primate model for investigating the neural basis …

Early life adversity (ELA), such as child maltreatment or child poverty, engenders problems
with emotional and behavioral regulation. In the quest to understand the neurobiological …

Accurately estimating safety is critical to pursuing nondefensive survival behaviors.
However, little attention has been paid to how the human brain computes safety. We …

The circadian clock regulates many biochemical and physiological pathways, and lack of
clock genes, such as Period (Per) 2, affects not only circadian activity rhythms, but can also …

Would you assess the performance of a soccer player by looking at them playing in the field
completely alone? Surely you would get overall information about their playing skills and …