[HTML][HTML] Neuroprotective natural products for Alzheimer's disease
X Chen, J Drew, W Berney, W Lei - Cells, 2021 - mdpi.com
Alzheimer's disease (AD) is the number one neurovegetative disease, but its treatment
options are relatively few and ineffective. In efforts to discover new strategies for AD therapy …
options are relatively few and ineffective. In efforts to discover new strategies for AD therapy …
[HTML][HTML] The cholinergic system, the adrenergic system and the neuropathology of Alzheimer's disease
RA Bekdash - International Journal of Molecular Sciences, 2021 - mdpi.com
Neurodegenerative diseases are a major public health problem worldwide with a wide
spectrum of symptoms and physiological effects. It has been long reported that the …
spectrum of symptoms and physiological effects. It has been long reported that the …
[HTML][HTML] Contemporary Transposon Tools: A Review and Guide through Mechanisms and Applications of Sleeping Beauty, piggyBac and Tol2 for Genome …
N Sandoval-Villegas, W Nurieva, M Amberger… - International journal of …, 2021 - mdpi.com
Transposons are mobile genetic elements evolved to execute highly efficient integration of
their genes into the genomes of their host cells. These natural DNA transfer vehicles have …
their genes into the genomes of their host cells. These natural DNA transfer vehicles have …
Cerebrolysin in the therapy of mild cognitive impairment and dementia due to Alzheimer's disease: 30 years of clinical use
SI Gavrilova, A Alvarez - Medicinal Research Reviews, 2021 - Wiley Online Library
Alzheimer's disease (AD) is the most common neurocognitive disorder and a global health
problem. The prevalence of AD is growing dramatically, especially in low‐and middle …
problem. The prevalence of AD is growing dramatically, especially in low‐and middle …
[HTML][HTML] Gene therapy in epilepsy
L Zhang, Y Wang - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Gene therapy may constitute a promising alternative to conventional pharmacological tools
and surgeries for epilepsy. For primary epilepsy, a single variant leading to a significant …
and surgeries for epilepsy. For primary epilepsy, a single variant leading to a significant …
[HTML][HTML] Bridging scales in alzheimer's disease: Biological framework for brain simulation with the virtual brain
Despite the acceleration of knowledge and data accumulation in neuroscience over the last
years, the highly prevalent neurodegenerative disease of AD remains a growing problem …
years, the highly prevalent neurodegenerative disease of AD remains a growing problem …
[HTML][HTML] Nerve growth factor biodelivery: a limiting step in moving toward extensive clinical application?
G Alastra, L Aloe, VA Baldassarro, L Calzà… - Frontiers in …, 2021 - frontiersin.org
Nerve growth factor (NGF) was the first-discovered member of the neurotrophin family, a
class of bioactive molecules which exerts powerful biological effects on the CNS and other …
class of bioactive molecules which exerts powerful biological effects on the CNS and other …
[HTML][HTML] Topical delivery of nerve growth factor for treatment of ocular and brain disorders
G Eftimiadi, M Soligo, L Manni, D Di Giuda… - Neural Regeneration …, 2021 - journals.lww.com
Neurotrophins are a family of proteins that support neuronal proliferation, survival, and
differentiation in the central and peripheral nervous systems, and are regulators of neuronal …
differentiation in the central and peripheral nervous systems, and are regulators of neuronal …
[HTML][HTML] Intranasal delivery of nerve growth factor in neurodegenerative diseases and neurotrauma
Since the 1980s, the development of a pharmacology based on nerve growth factor (NGF)
has been postulated for the therapy of Alzheimer's disease (AD). This hypothesis was based …
has been postulated for the therapy of Alzheimer's disease (AD). This hypothesis was based …
[HTML][HTML] CSF and plasma cholinergic markers in patients with cognitive impairment
A Karami, T Darreh-Shori, M Schultzberg… - Frontiers in Aging …, 2021 - frontiersin.org
Introduction Alzheimer's disease (AD) is the most prevalent form of dementia with symptoms
of deteriorating cognitive functions and memory loss, partially as a result of a decrease in …
of deteriorating cognitive functions and memory loss, partially as a result of a decrease in …