Atherosclerosis (AS) is a chronic disease with a complex pathology that may lead to several
cardiovascular and cerebrovascular diseases; however, further research is necessary to …

Breast cancer is one of the most common malignancies that seriously threaten women's
health. In the process of the malignant transformation of breast cancer, metabolic …

Metabolic reprogramming is considered hallmarks of cancer. Aerobic glycolysis in tumors
cells has been well-known for almost a century, but specific factors that regulate lactate …

It is well established that cancer cells acquire energy via the Warburg effect and oxidative
phosphorylation. Citrate is considered to play a crucial role in cancer metabolism by virtue of …

In cancer cells, metabolic adaptations are often observed in terms of nutrient absorption,
biosynthesis of macromolecules, and production of energy necessary to meet the needs of …

Alteration in glucose homeostasis during cancer metabolism is an important phenomenon.
Though several important transcription factors have been well studied in the context of the …

The breast tumor microenvironment is one of the crucial elements supporting breast cancer
tumor progression and metastasis. The fibroblasts are the chief cellular component of the …

The glycolytic modulator TP53-Inducible Glycolysis and Apoptosis Regulator (TIGAR) is
overexpressed in several types of cancer and has a role in metabolic rewiring during tumor …

Abstract TP53 (tumor protein 53)-induced glycolysis and apoptosis regulator (TIGAR)
belongs to the phosphatases family of proteins that modulates the level of reactive oxygen …

Head and neck squamous cell carcinoma (HNSCC) is the six most common cancer globally
and most common cancer in men in India. The metabolic regulation is highly altered and is …