Vessel-on-a-chip models for studying microvascular physiology, transport, and function in vitro
To understand how the microvasculature grows and remodels, researchers require
reproducible systems that emulate the function of living tissue. Innovative contributions …
reproducible systems that emulate the function of living tissue. Innovative contributions …
Review of OCT angiography findings in diabetic retinopathy: insights and perspectives
J Moir, S Khanna, D Skondra - International Journal of Translational …, 2021 - mdpi.com
Diabetes mellitus (DM), a disorder rapidly growing in prevalence, is linked to the retinal
microvasculature complication diabetic retinopathy (DR). As one of the leading global …
microvasculature complication diabetic retinopathy (DR). As one of the leading global …
Determining the parameter space for effective oxygen depletion for FLASH radiation therapy
BC Rothwell, NF Kirkby, MJ Merchant… - Physics in Medicine …, 2021 - iopscience.iop.org
There has been a recent revival of interest in the FLASH effect, after experiments have
shown normal tissue sparing capabilities of ultra-high-dose-rate radiation with no …
shown normal tissue sparing capabilities of ultra-high-dose-rate radiation with no …
A mesoscale computational model for microvascular oxygen transfer
L Possenti, A Cicchetti, R Rosati, D Cerroni… - Annals of Biomedical …, 2021 - Springer
We address a mathematical model for oxygen transfer in the microcirculation. The model
includes blood flow and hematocrit transport coupled with the interstitial flow, oxygen …
includes blood flow and hematocrit transport coupled with the interstitial flow, oxygen …
The capillary fascicle in skeletal muscle: Structural and functional physiology of RBC distribution in capillary networks
AA Mendelson, S Milkovich, T Hunter… - The Journal of …, 2021 - Wiley Online Library
Key points The capillary module, consisting of parallel capillaries from arteriole to venule, is
classically considered as the building block of complex capillary networks. In skeletal …
classically considered as the building block of complex capillary networks. In skeletal …
Morphological and functional relationship between OCTA and FA/ICGA quantitative features in AMD-related macular neovascularization
A Arrigo, E Aragona, A Bordato, A Amato… - Frontiers in …, 2021 - frontiersin.org
Background: The aim was to study the relationship between quantitative information
provided by optical coherence tomography (OCT) angiography (OCTA) and conventional …
provided by optical coherence tomography (OCT) angiography (OCTA) and conventional …
Do skeletal muscle motor units and microvascular units align to help match blood flow to metabolic demand?
CL Murrant, NM Fletcher, EJH Fitzpatrick… - European journal of …, 2021 - Springer
Purpose We explore the motor unit recruitment and control of perfusion of microvascular
units in skeletal muscle to determine whether they coordinate to match blood flow to …
units in skeletal muscle to determine whether they coordinate to match blood flow to …
Regenerated microvascular networks in ischemic skeletal muscle
H Yin, JM Arpino, JJ Lee, JG Pickering - Frontiers in Physiology, 2021 - frontiersin.org
Skeletal muscle is the largest organ in humans. The viability and performance of this
metabolically demanding organ are exquisitely dependent on the integrity of its …
metabolically demanding organ are exquisitely dependent on the integrity of its …
Quantitative optical coherence tomography angiography parameter variations after treatment of macular neovascularization secondary to age-related macular …
A Arrigo, E Aragona, A Bordato, A Amato, F Borghesan… - Retina, 2021 - journals.lww.com
Purpose: Macular neovascularization (MNV) secondary to age-related macular
degeneration can be characterized by quantitative optical coherence tomography …
degeneration can be characterized by quantitative optical coherence tomography …
A two-compartment model of oxygen transport in skeletal muscle using continuously distributed capillaries
KC Afas, R Vijay, D Goldman - Mathematical Biosciences, 2021 - Elsevier
For future application to studying regulation of microvascular oxygen delivery, a model is
developed for O 2 transport within an idealized volume of tissue, that is perfused by a …
developed for O 2 transport within an idealized volume of tissue, that is perfused by a …