Objective Identify disease categories in which single-item global impression (GI) scales
were included in product labeling of new drugs approved by the US Food and Drug …

Objectives To identify how refractory disease (or relevant terminology variations) in RA and
polyarticular JIA (polyJIA) is defined and establish the key components of such definitions …

Introduction This final analysis of a long-term extension (LTE) study assessed the safety,
tolerability, and effectiveness of peficitinib (ASP015K), a pan-Janus kinase inhibitor, in Asian …

Abstract Background Patient-reported outcomes (PROs) are increasingly used to track
symptoms and to assess disease activity, quality of life, and treatment effectiveness. It is …

Background A subcutaneous (SC) formulation of infliximab biosimilar CT-P13 is approved in
Europe for the treatment of adult patients with rheumatoid arthritis (RA). It may offer improved …

Over the last 30 years, treatment for RA has improved dramatically. By the early 2000s,
disease remission had become a realistic goal, although definitions of remission varied …

Abstract Background Peficitinib (ASP015K), a novel oral Janus kinase inhibitor, has
demonstrated efficacy and safety in the treatment of patients with rheumatoid arthritis (RA) …

One of the key challenges of personalized medicine is to identify which patients will respond
positively to a given treatment. The area of subgroup identification focuses on this challenge …

Knockoffs provide a general framework for controlling the false discovery rate when
performing variable selection. Much of the Knockoffs literature focuses on theoretical …

Objective Although mental disorder is one of the most common comorbidities of rheumatoid
arthritis (RA) and is known as a critical influence on RA remission rates, there is little …