Berberine improves cognitive impairment by simultaneously impacting cerebral blood flow and β-amyloid accumulation in an APP/tau/PS1 mouse model of …

C Ye, Y Liang, Y Chen, Y Xiong, Y She, X Zhong… - Cells, 2021 - mdpi.com
Alzheimer's disease (AD) is accompanied by β-amyloid (Aβ), neurofibrillary tangles, and
neuron cell death, and is one of the most commonly occurring diseases among the elderly …

RhoGEF17—An Essential Regulator of Endothelial Cell Death and Growth

P Weber, D Baltus, A Jatho, O Drews, LC Zelarayan… - Cells, 2021 - mdpi.com
The Rho guanine nucleotide exchange factor RhoGEF17 was described to reside in
adherens junctions (AJ) in endothelial cells (EC) and to play a critical role in the regulation …

Emerging roles of pericytes in coordinating skeletal muscle functions: implications and therapeutic potential

E Nwadozi, TL Haas - Current Tissue Microenvironment Reports, 2021 - Springer
Abstract Purpose of Review Capillaries are composed of endothelial cells that are partially
wrapped by a mural cell known as a pericyte. There is growing interest in the functional roles …

Exploring causes of pericyte expansion in postnatal brain of Rbpj-mediated mouse model of arteriovenous malformation

SM Kandalai - 2021 - rave.ohiolink.edu
Vascular function within the central nervous system is essential for cells, including those in
the brain, to function. Vascular abnormalities within the brain may lead to neurovascular …