As the population ages, the incidence of neurodegenerative diseases is increasing. Due to
intensive research, important steps in the elucidation of pathogenetic cascades have been …

Stroke is the leading cause of adult disability and death worldwide. Mitochondrial
dysfunction has been recognized as a marker of neuronal death during ischemic stroke …

Naringin is a flavonoid which has a therapeutic effect. However, the details of its antifungal
mechanism have not yet been fully elucidated. This study focused on clarifying the …

Mitochondrial quality control is crucial for sustaining cellular maintenance. Mitochondrial Ca
2+ plays an important role in the maintenance of mitochondrial quality control through …

Background: Diabetic Cardiomyopathy (DCM) has an adverse effect on health and occurs
with or without concurrent vascular disease. Although several pathological mechanisms …

Spinal cord injury (SCI) is characterized by vascular disruption leading to ischemia,
decreased oxygen delivery and loss of mitochondrial homeostasis. The dysregulation …

Mitochondria are highly dynamic organelles that undergo morphological changes through a
system of fission and fusion. Throughout interphase mitochondria primarily exist as large …

Cancer cachexia is defined as the unintentional loss of skeletal muscle mass with or without
fat loss that cannot be reversed by conventional nutritional support. Cachexia occurs in …

The tumor microenvironment is highly heterogenous and composed of tumor cells and
various immune effector cells. Tumor-associated macrophages (TAMs) are essential …