Tumorigenic aspects of MSC senescence—implication in cancer development and therapy
As an organism ages, many physiological processes change, including the immune system.
This process, called immunosenescence, characterized by abnormal activation and …
This process, called immunosenescence, characterized by abnormal activation and …
Inhibition of miR-199a-5p rejuvenates aged mesenchymal stem cells derived from patients with idiopathic pulmonary fibrosis and improves their therapeutic efficacy in …
L Shi, Q Han, Y Hong, W Li, G Gong, J Cui… - Stem Cell Research & …, 2021 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is an age-related disease with no cure.
Mesenchymal stem cell (MSC)-based therapy has emerged as a novel strategy for IPF …
Mesenchymal stem cell (MSC)-based therapy has emerged as a novel strategy for IPF …
Human endometrium-derived stem cell improves cardiac function after myocardial ischemic injury by enhancing angiogenesis and myocardial metabolism
Background The human endometrium in premenopausal women is an active site of
physiological angiogenesis, with regenerative cells present, suggesting that the …
physiological angiogenesis, with regenerative cells present, suggesting that the …
Apelin rejuvenates aged human mesenchymal stem cells by regulating autophagy and improves cardiac protection after infarction
H Zhang, C Zhao, G Jiang, B Hu, H Zheng… - Frontiers in Cell and …, 2021 - frontiersin.org
The protective effects of mesenchymal stem cell (MSC)-based therapy for myocardial
infarction (MI) are largely hampered as they age. Apelin is an endogenous ligand of its …
infarction (MI) are largely hampered as they age. Apelin is an endogenous ligand of its …
In Vivo supportive effects of mesenchymal stem cells on fat graft stabilization and local induction of angiogenesis are not dependent on the cell donor age or in vitro …
K Siennicka, P Piotrowski, W Olszewski… - Rejuvenation …, 2021 - liebertpub.com
Mesenchymal stromal cells from adipose tissue (adipose stromal cells, ASCs) are regulators
of repair processes in situ by paracrine mechanisms. These unique capabilities make ASCs …
of repair processes in situ by paracrine mechanisms. These unique capabilities make ASCs …