Multiple targets for oxysterols in their regulation of the immune system

L Reinmuth, CC Hsiao, J Hamann, M Rosenkilde… - Cells, 2021 - mdpi.com
Oxysterols, or cholesterol oxidation products, are naturally occurring lipids which regulate
the physiology of cells, including those of the immune system. In contrast to effects that are …

Functional heterogeneity and adaptation of naive T cells in response to tonic TCR signals

J Eggert, BB Au-Yeung - Current opinion in immunology, 2021 - Elsevier
Highlights•Surrogate markers of tonic TCR signaling include CD5, Ly6C, and Nur77-
GFP.•Tonic (or basal) TCR signaling in response to self-antigens can vary in intensity.•Naive …