Insights on functionalized carbon nanotubes for cancer theranostics

L Tang, Q Xiao, Y Mei, S He, Z Zhang, R Wang… - Journal of …, 2021 - Springer
Despite the exciting breakthroughs in medical technology, cancer still accounts for one of
the principle triggers of death and conventional therapeutic modalities often fail to attain an …

Low-dose targeted radionuclide therapy renders immunologically cold tumors responsive to immune checkpoint blockade

RB Patel, R Hernandez, P Carlson… - Science translational …, 2021 - science.org
Molecular and cellular effects of radiotherapy on tumor microenvironment (TME) can help
prime and propagate antitumor immunity. We hypothesized that delivering radiation to all …

[HTML][HTML] Treatment with radiopharmaceuticals and radionuclides in breast cancer: Current options

BA Güleç, F Yurt - European Journal of Breast Health, 2021 - ncbi.nlm.nih.gov
Radiopharmaceutical therapy (RPT) is an effective and safe treatment for many types of
cancer. RPT acts by binding radioactive atoms to tumor-associated antigens, monoclonal …

Cyclotron-produced 132La as a PET imaging surrogate for therapeutic 225Ac

E Aluicio-Sarduy, TE Barnhart, J Weichert… - Journal of Nuclear …, 2021 - Soc Nuclear Med
The aim of this work was to explore 132La as a PET imaging surrogate for 225Ac using a
DOTA-based, tumor-targeting alkylphosphocholine (NM600). Methods: 132La was …

Low-Dose Radiation Potentiates the Propagation of Anti-Tumor Immunity against Melanoma Tumor in the Brain after In Situ Vaccination at a Tumor outside the Brain

PA Clark, RN Sriramaneni, AM Bates… - Radiation …, 2021 - meridian.allenpress.com
Brain metastases develop in over 60% of advanced melanoma patients and negatively
impact quality of life and prognosis. In a murine melanoma model, we previously showed …

[PDF][PDF] Investigation of Folate-Based Radiopharmaceuticals for Theragnostic Application and Combination Therapy

P Guzik - 2021 - research-collection.ethz.ch
The folate receptor-α (FRα) is a cell membrane-associated protein which has been used for
targeted therapies in oncology [24]. Among FRα-expressing malignancies are gynecologic …