The tumor microenvironment (TME) is a critical regulator of tumor growth, progression, and
metastasis. Since immune cells represent a large fraction of the TME, they play a key role in …

Breast cancer was traditionally not considered a particularly immunogenic tumor. However,
recent developments have shown that some aggressive triple-negative breast cancers are …

Recent preclinical and clinical data suggests enhanced metastatic fitness of hybrid
epithelial/mesenchymal (E/M) phenotypes, but mechanistic details regarding their survival …

Background & Aims In autoimmune hepatitis (AIH), the imbalance between regulatory T cells
(Tregs) and T-helper type 17 (Th17) cells has been linked to low levels of CD39, an …

Breast cancer, a hormone‐dependent tumour, generally includes four molecular subtypes
(luminal A, luminal B, HER2 enriched and triple‐negative) based on oestrogen receptor …

As the essential sexual hormone, estrogen and its receptor has been proved to participate in
the regulation of autoimmunity diseases and anti-tumor immunity. The adjustment of tumor …

Simple Summary Programmed cell death ligand 1 (PD-L1) is an essential immune
checkpoint molecule that helps tumor cells to escape the immune surveillance. The aim of …

Introduction Estrogen receptors (ESRs) and progesterone receptors (PGRs) are associated
with the development and progression of various tumors. The feasibility of ESRs and PGRs …

Abstract Apolipoprotein AI (ApoA-I), the main protein component of high-density lipoprotein
(HDL), plays a pivotal role in reverse cholesterol transport (RCT). Previous studies indicated …

Breast cancer is one of the most commonly diagnosed malignancies. Although endocrine
therapy improves the survival of patients with hormone receptor (HR)-positive breast cancer …