Immunosuppressive mechanisms of regulatory B cells

D Catalán, MA Mansilla, A Ferrier, L Soto… - Frontiers in …, 2021 - frontiersin.org
Regulatory B cells (Bregs) is a term that encompasses all B cells that act to suppress
immune responses. Bregs contribute to the maintenance of tolerance, limiting ongoing …

Regulatory b cells, a to z

K Jansen, L Cevhertas, S Ma, P Satitsuksanoa… - Allergy, 2021 - Wiley Online Library
B cells play a central role in the immune system through the production of antibodies. During
the past two decades, it has become increasingly clear that B cells also have the capacity to …

Revisiting the mechanisms of immune evasion employed by human parasites

M Chulanetra, W Chaicumpa - Frontiers in cellular and infection …, 2021 - frontiersin.org
For the establishment of a successful infection, ie, long-term parasitism and a complete life
cycle, parasites use various diverse mechanisms and factors, which they may be inherently …

IL-10 as a Th2 cytokine: differences between mice and humans

MT Rasquinha, M Sur, N Lasrado… - The Journal of …, 2021 - journals.aai.org
The discovery of IL-10 more than 30 years ago marked the beginning of our understanding
of how cytokines regulate immune responses, based on cross-regulation between Th1 and …

Schistosome immunomodulators

S Acharya, AA Da'dara, PJ Skelly - PLoS Pathogens, 2021 - journals.plos.org
Schistosomes are long lived, intravascular parasitic platyhelminths that infect> 200 million
people globally. The molecular mechanisms used by these blood flukes to dampen host …

Schistosomes in the lung: immunobiology and opportunity

EL Houlder, AH Costain, PC Cook… - Frontiers in …, 2021 - frontiersin.org
Schistosome infection is a major cause of global morbidity, particularly in sub-Saharan
Africa. However, there is no effective vaccine for this major neglected tropical disease, and …

Macrophage regulation & function in helminth infection

A Lechner, S Bohnacker, J Esser-von Bieren - Seminars in immunology, 2021 - Elsevier
Macrophages are innate immune cells with essential roles in host defense, inflammation,
immune regulation and repair. During infection with multicellular helminth parasites …

Regulatory B cells in respiratory health and diseases

M Menon, T Hussell, H Ali Shuwa - Immunological reviews, 2021 - Wiley Online Library
B cells are critical mediators of humoral immune responses in the airways through antibody
production, antigen presentation, and cytokine secretion. In addition, a subset of B cells …

B regulatory cells in allergy

S Ma, P Satitsuksanoa, K Jansen… - Immunological …, 2021 - Wiley Online Library
B cells have classically been recognized for their unique and indispensable role in the
production of antibodies. Their potential as immunoregulatory cells with anti‐inflammatory …

Regulatory B cells control airway hyperreactivity and lung remodeling in a murine asthma model

A Habener, C Happle, R Grychtol, J Skuljec… - Journal of Allergy and …, 2021 - Elsevier
Background Asthma is a widespread, multifactorial chronic airway disease. The influence of
regulatory B cells on airway hyperreactivity (AHR) and remodeling in asthma is poorly …