Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …

DNA nanotechnology has produced a wide range of self-assembled structures, offering
unmatched possibilities in terms of structural design. Because of their programmable …

Microplastics (MPs) considered as a new persistent environmental pollutant could enter into
the circulatory system and result in decrease of sperm quantity and quality in mice. However …

Using the DNA origami technique, we constructed a DNA nanodevice functionalized with
small interfering RNA (siRNA) within its inner cavity and the chemotherapeutic drug …

Bladder cancer is one of the concerning malignancies worldwide, which is lacking effective
targeted therapy. Gene therapy is a potential approach for bladder cancer treatment. While …

The field of structural DNA nanotechnology applies the programmability of Watson-Crick
base pairing to the construction of custom nanostructures that are prescribed by the …

Chemically modified DNA has been widely developed to fabricate various nucleic acid
nanostructures for biomedical applications. Herein, we report a facile strategy for …

DNA-based nanogels have attracted much attention in the biomedical research field. Herein,
we report a universal strategy for the fabrication of an aptamer-modified DNA tetrahedron …

Although chemotherapy and photothermal therapy are widely used to combat cancer, their
efficacy is often limited by multidrug resistance. Small interfering RNAs (siRNAs) have ability …

Nucleic acid nanostructures are promising biomaterials for the delivery of homologous gene
therapy drugs. Herein, we report a facile strategy for the construction of target mRNA …