Immunotherapy has revolutionized cancer treatment, but efficacy remains limited in most
clinical settings. Cancer is a systemic disease that induces many functional and …

Viral infections can give rise to a systemic decrease in the total number of lymphocytes in the
blood, referred to as lymphopenia. Lymphopenia may affect the host adaptive immune …

Purpose Emerging evidence suggests a detrimental prognostic association between
radiation-induced lymphopenia (RIL) and pathologic response, progression-free survival …

Blood cell counts often fail to report on immune processes occurring in remote tissues. Here,
we use immune cell type-specific methylation patterns in circulating cell-free DNA (cfDNA) …

This study aimed to investigate the distribution laws and research frontiers of international
literature, so as to present a holistic bibliometric evaluation of the studies on breast cancer …

Background Despite the modern advances in treatment techniques, the survival of locally
advanced lung cancer patients continues to remain poor. Circulating lymphocytes have an …

Purpose: N-803 is an IL15 receptor superagonist complex, designed to optimize in vivo
persistence and trans-presentation, thereby activating and expanding natural killer (NK) …

The efficacy of current treatment regimens for pancreatic cancer (PC) remains unsatisfactory.
In recent years, immune checkpoint blockade (ICB) therapy has shown promising anti-tumor …

Background: The prognostic nutritional index (PNI) is related to the prognosis of multiple
malignancies. This study investigated whether the PNI has prognostic value in advanced …

The systemic inflammation response index (SIRI) has been revealed to be closely related to
the prognosis of a variety of tumors. Whether the dynamic change in SIRI before and after …