Extra-motor cerebral changes and manifestations in primary lateral sclerosis

E Finegan, SLH Shing, RH Chipika, KM Chang… - Brain imaging and …, 2021 - Springer
Primary lateral sclerosis (PLS) is classically considered a 'pure'upper motor neuron disorder.
Motor cortex atrophy and pyramidal tract degeneration are thought to be pathognomonic of …

[HTML][HTML] Cognitive network hyperactivation and motor cortex decline correlate with ALS prognosis

R McMackin, S Dukic, E Costello, M Pinto-Grau… - Neurobiology of …, 2021 - Elsevier
We aimed to quantitatively characterize progressive brain network disruption in Amyotrophic
Lateral Sclerosis (ALS) during cognition using the mismatch negativity (MMN), an …