Many approaches have been used in the effective management of type 2 diabetes mellitus.
A recent paradigm shift has focused on the role of adipose tissues in the development and …

Skeletal muscle possesses dramatic metabolic plasticity that allows for the rapid adaptation
in cellular energy transduction to meet the demands of the organism. Obesity elicits changes …

During aging, body adiposity increases with changes in the metabolism of lipids and their
metabolite levels. Considering lipid metabolism, excess adiposity with increased lipotoxicity …

Comparing energy metabolism in human skeletal muscle and primary skeletal muscle cells
in obesity, while focusing on glucose and fatty acid metabolism, shows many common …

Skeletal muscle has the remarkable ability to regenerate. However, with age and disease
muscle strength and function decline. Myofiber size, which is affected by injury and disease …

A sedentary lifestyle is associated with overweight/obesity, which involves excessive fat
body accumulation, triggering structural and functional changes in tissues, organs, and body …

The impact of brown adipose tissue (BAT) metabolism on understanding energy balance in
humans is a relatively new and exciting field of research. The pathogenesis of obesity can …

Obesity is an increasing public health concern both in the developed and developing
countries. Previous studies have demonstrated that considerable alterations in lipid …

Context Impaired lipid metabolism is linked with obesity-associated insulin resistance, which
may be reversed by caloric restriction (CR). Objective In a secondary analysis of a …

In obesity, accumulation of lipid droplets in skeletal muscle fibers and a shift towards fast
muscle fiber types can both contribute to insulin resistance. However, it is not yet clear how …