Attribution of NF-κB activity to CHUK/IKKα-involved carcinogenesis

X Li, Y Hu - Cancers, 2021 - mdpi.com
Simple Summary CHUK/IKKα has emerged as a novel tumor suppressor in several organs
of humans and mice. In general, activation of NF-κB promotes inflammation and …

Genetically engineered mouse models of esophageal cancer

RA Mahmoudian, M Farshchian… - Experimental cell …, 2021 - Elsevier
Background Esophageal cancer is the most common cause of cancer-related death
worldwide with a diverse geographical distribution, poor prognosis, and diagnosis in …

[HTML][HTML] IκB Kinase-β regulates neutrophil recruitment through activation of STAT3 signaling in the esophagus

KN Wiles, CM Alioto, NB Hodge, MH Clevenger… - Cellular and Molecular …, 2021 - Elsevier
Background & Aims The epithelial barrier is the host's first line of defense against damage to
the underlying tissue. Upon injury, the epithelium plays a critical role in inflammation. The …