In eukaryotic cells, proteins are targeted to their final subcellular locations with precise
timing. A key underlying mechanism is the active transport of cognate mRNAs, which in …

Highlights•Upf1 targets viral RNAs for degradation through multiple pathways.•Viruses
disrupt Upf1-mediated decay in different way through cis-acting and trans-acting …

Stau1 is a pluripotent RNA-binding protein that is responsible for the post-transcriptional
regulation of a multitude of transcripts. Here, we observed that lung cancer patients with a …

RNA is a central molecule in RNA virus biology due to its dual function as messenger and
genome. However, the small number of proteins encoded by viral genomes is insufficient to …

Abstract The Nonsense-mediated mRNA Decay (NMD) pathway is an RNA quality control
pathway conserved among eukaryotic cells. While historically thought to predominantly …

In recent years, an increasing number of reports have linked the RNA‐binding protein
Staufen1 (STAU1) to the control of cell decision making. In non‐transformed cells, STAU1 …

Staufen, the RNA-binding family of proteins, affects various steps in the Human Immuno-
Deficiency Virus (HIV-1) replication cycle. While our previous study established Staufen-2 …

As a highly pathogenic influenza virus, H5N1 avian influenza virus (AIV) poses a great threat
to poultry production and public health. H5N1 AIV has a small genome and, therefore, relies …

In this study, we investigated how Staufen1 influences the HIV-1 production. The
overexpression of Staufen1 increased virus production without any negative affect on the …