Aptamer-based detection of circulating targets for precision medicine
L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …
[HTML][HTML] Regulation of exosome production and cargo sorting
H Wei, Q Chen, L Lin, C Sha, T Li, Y Liu… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Cellular communication can be mediated by the exchange of biological information, mainly
in the form of proteins and RNAs. This can occur when extracellular vesicles, such as …
in the form of proteins and RNAs. This can occur when extracellular vesicles, such as …
Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin
RE Veerman, L Teeuwen, P Czarnewski… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are increasingly tested as therapeutic vehicles and biomarkers,
but still EV subtypes are not fully characterised. To isolate EVs with few co‐isolated entities …
but still EV subtypes are not fully characterised. To isolate EVs with few co‐isolated entities …
Advances and utility of the human plasma proteome
The study of proteins circulating in blood offers tremendous opportunities to diagnose,
stratify, or possibly prevent diseases. With recent technological advances and the urgent …
stratify, or possibly prevent diseases. With recent technological advances and the urgent …
Towards microfluidic-based exosome isolation and detection for tumor therapy
Exosomes are a class of cell-secreted, nano-sized extracellular vesicles with a bilayer
membrane structure of 30–150 nm in diameter. Their discovery and application have …
membrane structure of 30–150 nm in diameter. Their discovery and application have …
A comprehensive review on factors influences biogenesis, functions, therapeutic and clinical implications of exosomes
S Gurunathan, MH Kang, JH Kim - International journal of …, 2021 - Taylor & Francis
Exosomes are nanoscale-sized membrane vesicles secreted by almost all cell types into the
extracellular environment upon fusion of multivesicular bodies and plasma membrane …
extracellular environment upon fusion of multivesicular bodies and plasma membrane …
Exosomes as naturally occurring vehicles for delivery of biopharmaceuticals: insights from drug delivery to clinical perspectives
A Butreddy, N Kommineni, N Dudhipala - Nanomaterials, 2021 - mdpi.com
Exosomes as nanosized vesicles are emerging as drug delivery systems for therapeutics
owing to their natural origin, their ability to mediate intercellular communication, and their …
owing to their natural origin, their ability to mediate intercellular communication, and their …
The role of exosomes in liquid biopsy for cancer diagnosis and prognosis prediction
S Li, M Yi, B Dong, X Tan, S Luo… - International journal of …, 2021 - Wiley Online Library
Liquid biopsy is a revolutionary strategy in cancer diagnosis and prognosis prediction, which
is used to analyze cancer cells or cancer‐derived products through biofluids such as blood …
is used to analyze cancer cells or cancer‐derived products through biofluids such as blood …
Recent progress in detection and profiling of cancer cell‐derived exosomes
H Xiong, Z Huang, Z Yang, Q Lin, B Yang, X Fang… - Small, 2021 - Wiley Online Library
Exosomes, known as nanometer‐sized vesicles (30–200 nm), are secreted by many types of
cells. Cancer‐derived exosomes have great potential to be biomarkers for early clinical …
cells. Cancer‐derived exosomes have great potential to be biomarkers for early clinical …
[HTML][HTML] Exosomes in atherosclerosis: performers, bystanders, biomarkers, and therapeutic targets
C Wang, Z Li, Y Liu, L Yuan - Theranostics, 2021 - ncbi.nlm.nih.gov
Exosomes are nanosized lipid vesicles originating from the endosomal system that carry
many macromolecules from their parental cells and play important roles in intercellular …
many macromolecules from their parental cells and play important roles in intercellular …