Pancreatic cancer is an increasingly common cause of cancer mortality with a tight
correspondence between disease mortality and incidence. Furthermore, it is usually …

Pancreatic cancer is a genetic disease, and the recurrent genetic alterations characteristic of
pancreatic cancer indicate the cellular processes that are targeted for malignant …

Intratumoral heterogeneity is a critical frontier in understanding how the tumor
microenvironment (TME) propels malignant progression. Here, we deconvolute the human …

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor patient
survival. Toward understanding the underlying molecular alterations that drive PDAC …

The current pathological and molecular classification of pancreatic ductal adenocarcinoma
(PDAC) provides limited guidance for treatment options, especially for immunotherapy …

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive form of cancer with a dismal
prognosis. The lack of symptoms in the early phase of the disease makes early diagnosis …

Prognostically relevant RNA expression states exist in pancreatic ductal adenocarcinoma
(PDAC), but our understanding of their drivers, stability, and relationship to therapeutic …

Complex rearrangement patterns and mitotic errors are hallmarks of most pancreatic ductal
adenocarcinomas (PDAC), a disease with dismal prognosis despite some therapeutic …

Large-scale genomic profiling of pancreatic cancer (PDAC) has revealed two distinct
subtypes:'classical'and 'basal-like'. Their variable coexistence within the stromal immune …

Activating RAS missense mutations are among the most prevalent genomic alterations
observed in human cancers and drive oncogenesis in the three most lethal tumor types …