Protein arginine methyltransferases (PRMTs) are emerging as attractive therapeutic targets.
PRMTs regulate transcription, splicing, RNA biology, the DNA damage response and cell …

Majority of the human genome is transcribed to RNAs that do not encode proteins. These
non-coding RNAs (ncRNAs) play crucial roles in regulating the initiation and progression of …

Background Increasing studies have shown that long noncoding RNAs (lncRNAs) are
pivotal regulators participating in carcinogenic progression and tumor metastasis in …

Abstract Aberrant N 6-methyladenosine (m6A) modification has emerged as a driver of
tumor initiation and progression, yet how long noncoding RNAs (lncRNA) are involved in the …

Liver disease, particularly viral hepatitis and hepatocellular carcinoma (HCC), is a global
healthcare burden and leads to more than 2 million deaths per year worldwide. Despite …

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths
worldwide. HCC has high rates of death and recurrence, as well as very low survival rates …

Krüppel-like factor 5 (KLF5) is an oncogenic factor that is highly expressed in basal-like
breast cancer (BLBC) and promotes cell proliferation, survival, migration, stemness, and …

The insulin-like growth factor-2 mRNA-binding proteins (IGF2BPs) pertain to a highly
conservative RNA-binding family that works as a post-transcriptional fine-tuner for target …

Because of the lack of sensitivity to radiotherapy and chemotherapy, therapeutic options for
renal clear cell carcinoma (KIRC) are scarce. Long noncoding RNAs (lncRNAs) play crucial …

Hepatocellular carcinoma (HCC) is a prevalent human malignancy with high morbidity
worldwide. Hepatocarcinogenesis is a complex multistep process, and its underlying …