Simple Summary Integrins, a superfamily of cell adhesion receptors, were extensively
investigated as therapeutic targets over the last decades, motivated by their multiple …

Enabling angiogenesis is critical for the success of tissue repair therapies and the fate of
tissue-engineered constructs. Although many biochemical signaling molecules have been …

Integrins are transmembrane receptors that have been implicated in the biology of various
human physiological and pathological processes. These molecules facilitate cell …

Carriers of genetic material are divided into vectors of viral and non-viral origin. Viral carriers
are already successfully used in experimental gene therapies, but despite advantages such …

Integrins are a class of transmembrane receptors that are involved in a wide range of
biological functions. Dysregulation of integrins has been implicated in many pathological …

Integrin activation contributes to key blood cell functions including adhesion, proliferation
and migration. An essential step in the cell signaling pathway that activates integrin requires …

Developments in tissue engineering techniques have allowed for the creation of
biocompatible, non-immunogenic alternative vascular grafts through the decellularization of …

Simple Summary Cancer growth and metastasis require interactions with the extracellular
matrix (ECM), which is home to many biomolecules that support the formation of new …

Gestational diabetes mellitus (GDM) is a major pregnancy-related disorder with an
increasing prevalence worldwide. GDM is associated with altered placental vascular …

The interactions between cells and their extracellular matrix (ECM) are critically important for
homeostatic control of cell growth, proliferation, differentiation and apoptosis …