Cisplatin is a potent platinum-based anticancer drug approved by the Food Drug
Administration (FDA) in 1978. Despite its advantages against solid tumors, cisplatin confers …

Advancements in cancer therapy increased the cancer free survival rates and reduced the
malignant related deaths. Therapeutic options for patients with thoracic cancers include …

Cardiotoxicity has been well documented as a side effect of cisplatin (CDDP) treatment. The
inflammatory response plays a crucial role in the pathological process of CDDP-induced …

Cisplatin is an efficient anticancer drug against various types of cancers however, its usage
involves side effects. We investigated the mechanisms of action of indole derivative, 2-(5 …

Cardiovascular toxicity remains one of the most adverse side effects in cancer patients
receiving chemotherapy. Extra-virgin olive oil (EVOO) is rich in cancer preventive …

Cisplatin is an efficacious anticancer agent, but its use is limited by ototoxicity and resultant
irreversible sensorineural hearing loss. Cisplatin ototoxicity is associated with cochlear cell …

Cardiovascular complications have been well documented as the downside to conventional
cancer chemotherapy. As a notable side effect of cisplatin (CDDP), cardiotoxicity represents …

Cardiotoxicity is a well-recognised side effect of cancer-related therapies with a great impact
on outcomes and quality of life in the cancer survivor population. The pathogenesis of …

Cardiovascular complications are a well-documented limitation of conventional cancer
chemotherapy. As a notable side effect of cisplatin, cardiotoxicity represents a major …

Ruthenium (II) complexes offer the potential for lower toxicity compared with platinum (II)
complexes. Our study aimed to compare cardiotoxicity of [Ru (Cl-tpy)(en) Cl][Cl],[Ru (Cl …