Acute respiratory distress syndrome (ARDS) is a serious complication of severe systemic or
local pulmonary inflammation, such as caused by severe acute respiratory syndrome …

Pulmonary hypertension is the term used to describe a group of disorders characterized by
abnormally high pressures in the pulmonary arteries. Initial evaluation is focused on …

Background The benefit of sildenafil in patients with advanced idiopathic pulmonary fibrosis
(IPF) at risk of poor outcomes from pulmonary hypertension, whether already present or …

Background The purpose of this study was to screen various drug delivery systems for
improving the aqueous solubility and oral bioavailability of sildenafil. Three representative …

Objective To identify secular trends associated with systemic sclerosis (SSc) mortality over a
48‐year period. Methods Using national mortality data compiled by the Centers for Disease …

Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease where the additional presence of
pulmonary hypertension (PH) reduces survival. In particular, the presence of coexistent …

Background: There is limited evidence for pulmonary arterial hypertension (PAH)-targeted
therapy in patients with pulmonary hypertension associated with respiratory disease (R-PH) …

Managing patients with pulmonary hypertension (PH) in association with chronic lung
disease and/or hypoxia (PH-CLD) remains one of the most challenging areas in pulmonary …

Idiopathic pulmonary fibrosis (IPF) remains an intractably fatal disorder, despite the recent
advent of anti-fibrotic medication. Successful treatment of IPF, like many chronic diseases …

Since its description by Romberg in 1891, 1 pulmonary arterial hypertension (PAH) was a
disease with low incidence and prevalence. However, in the 1960s a surge in PAH cases …