Hydroxyapatite nanoparticles in drug delivery: physicochemistry and applications

S Lara-Ochoa, W Ortega-Lara, CE Guerrero-Beltrán - Pharmaceutics, 2021 - mdpi.com
Hydroxyapatite (HAP) has been the gold standard in the biomedical field due to its
composition and similarity to human bone. Properties such as shape, size, morphology, and …

Design and development of hybrid hydrogels for biomedical applications: Recent trends in anticancer drug delivery and tissue engineering

MH Cai, XY Chen, LQ Fu, WL Du, X Yang… - … in Bioengineering and …, 2021 - frontiersin.org
The applications of hydrogels in biomedical field has been since multiple decades.
Discoveries in biology and chemistry render this platform endowed with much engineering …

Nexus between in silico and in vivo models to enhance clinical translation of nanomedicine

FM Kashkooli, M Soltani, M Souri, C Meaney… - Nano Today, 2021 - Elsevier
In cancer, one of the main barriers to effective chemotherapy is inefficient drug delivery. The
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …

APTES monolayer coverage on self-assembled magnetic nanospheres for controlled release of anticancer drug Nintedanib

VC Karade, A Sharma, RP Dhavale, RP Dhavale… - Scientific Reports, 2021 - nature.com
The use of an appropriate delivery system capable of protecting, translocating, and
selectively releasing therapeutic moieties to desired sites can promote the efficacy of an …

Gain an advantage from both sides: Smart size-shrinkable drug delivery nanosystems for high accumulation and deep penetration

S Bai, Y Zhang, D Li, X Shi, G Lin, G Liu - Nano Today, 2021 - Elsevier
The first generation of nanomedicine exhibits superior performance in the clinical treatment
of various cancers compared to free conventional anticancer therapeutics. However, poor …

Nano-scale delivery: A comprehensive review of nano-structured devices, preparative techniques, site-specificity designs, biomedical applications, commercial …

AAH Abdellatif, HA Mohammed, RA Khan… - Nanotechnology …, 2021 - degruyter.com
This review focuses on nano-structured delivery devices prepared from biodegradable and
biocompatible natural and synthetic polymers, organic raw materials, metals, metal oxides …

Virus-inspired nanosystems for drug delivery

Z Liao, L Tu, X Li, XJ Liang, S Huo - Nanoscale, 2021 - pubs.rsc.org
With over millions of years of evolution, viruses can infect cells efficiently by utilizing their
unique structures. Similarly, the drug delivery process is designed to imitate the viral …

Systematic characterization of nanostructured lipid carriers from cetyl palmitate/caprylic triglyceride/tween 80 mixtures in an aqueous environment

N Izza, K Suga, Y Okamoto, N Watanabe, TT Bui… - Langmuir, 2021 - ACS Publications
Nanostructured lipid carriers (NLCs) are gaining attention as the new generation of lipid
vehicles. These carriers consist of saturated lipids with small drops of liquid oil dispersed …

Digital blood in massively parallel CPU/GPU systems for the study of platelet transport

C Kotsalos, J Latt, J Beny, B Chopard - Interface Focus, 2021 - royalsocietypublishing.org
We propose a highly versatile computational framework for the simulation of cellular blood
flow focusing on extreme performance without compromising accuracy or complexity. The …

Multifunctional ZnO@ CuS nanoparticles cluster synergize chemotherapy and photothermal therapy for tumor metastasis

H Deng, Y Yang, T Zuo, T Fang, Y Xu, J Yang… - … , Biology and Medicine, 2021 - Elsevier
The poor drug delivery and unsatisfying therapeutic effects remain to be the primary
challenges for cancer therapy. Nanosystem that combines multiple functions into a single …