The evaluation and management of monoclonal gammopathy of renal significance and monoclonal gammopathy of neurological significance

JJ Castillo, NS Callander, M Baljevic… - American journal of …, 2021 - Wiley Online Library
Despite the benign nature of monoclonal gammopathy of undetermined significance
(MGUS), mounting data are associating MGUS with the development of organ dysfunction …

Isatuximab plus pomalidomide and dexamethasone in relapsed/refractory multiple myeloma patients with renal impairment: ICARIA-MM subgroup analysis

MA Dimopoulos, X Leleu, P Moreau, PG Richardson… - Leukemia, 2021 - nature.com
The randomized, phase 3 ICARIA-MM study investigated isatuximab (Isa) with
pomalidomide and dexamethasone (Pd) versus Pd in patients with relapsed/refractory …

Effect of high cut-off dialysis for acute kidney injury secondary to cast nephropathy in patients with multiple myeloma: a systematic review and meta-analysis

B Tarragon, N Ye, M Gallagher, S Sen… - Clinical Kidney …, 2021 - academic.oup.com
Background Acute kidney injury (AKI) caused by cast nephropathy is associated with
increased morbidity and mortality among patients with multiple myeloma (MM). High cut-off …

Incidence, prognostic impact and clinical outcomes of renal impairment in patients with multiple myeloma: a population-based registry

M Courant, S Orazio, A Monnereau… - Nephrology Dialysis …, 2021 - academic.oup.com
Background Renal impairment (RI), a severe complication in multiple myeloma (MM), is
considered as a poor prognostic factor. Patient survival has increased with the use of novel …

Anti-BCMA CAR-T cell therapy in relapsed or refractory multiple myeloma patients with impaired renal function

S He, Y Cheng, D Wang, M Xu, Y Que, Y Xu, L Ma… - Current Medical …, 2021 - Springer
Anti-B cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T-cell therapy is
effective and well-tolerated for refractory or relapsed multiple myeloma (RRMM). The …

Kinetics of renal function during induction in newly diagnosed multiple myeloma: results of two prospective studies by the German Myeloma Study Group DSMM

F Bachmann, M Schreder, M Engelhardt, C Langer… - Cancers, 2021 - mdpi.com
Simple Summary Renal insufficiency is frequently seen in newly diagnosed multiple
myeloma and can be due to the disease itself but also caused by medical interventions or …

Full or intensity‐reduced high‐dose melphalan and single or double autologous stem cell transplant with or without bortezomib consolidation in patients with newly …

C Straka, H Salwender, S Knop, M Vogel… - European Journal of …, 2021 - Wiley Online Library
Objective A post hoc subgroup analysis of two phase III trials (NCT00416273,
NCT00416208) was carried out to investigate the influence of 100/140 and 200 mg/m² …

[HTML][HTML] Supportive treatment for cast nephropathy in patients with multiple myeloma; a pilot study

G Cancarini, V Terlizzi, A Garatti… - Journal of …, 2021 - jnephropharmacology.com
Introduction: Cast nephropathy is a prevalent cause of acute kidney injury (AKI) in patients
with myeloma. Objectives: The aim of this study is to define the outcome of a standardized …

Crystalline deposits in the cornea and various areas of the kidney as symptoms of an underlying monoclonal gammopathy: a case report

C Lindemann, P Enders, PT Brinkkoetter, LA Völker - BMC nephrology, 2021 - Springer
Background Plasma cell dyscrasias (PCD) are characterized by an abnormal production of
intact monoclonal immunoglobulins or parts such as heavy or light chains. In most cases, the …

[图书][B] Bone remodeling process: mechanics, biology, and numerical modeling

RB Kahla, A Barkaoui - 2021 - books.google.com
Bone Remodeling Process: Mechanics, Biology, and Numerical Modeling provides a
literature review. The first part of the book discusses bones in a normal physiological …