[HTML][HTML] Targeting glioblastoma stem cells: a review on biomarkers, signal pathways and targeted therapy

X Tang, C Zuo, P Fang, G Liu, Y Qiu, Y Huang… - Frontiers in …, 2021 - frontiersin.org
Glioblastoma (GBM) remains the most lethal and common primary brain tumor, even after
treatment with multiple therapies, such as surgical resection, chemotherapy, and radiation …

[HTML][HTML] Hepatic stellate cells: current state and open questions

C Kordes, HH Bock, D Reichert, P May… - Biological …, 2021 - degruyter.com
This review article summarizes 20 years of our research on hepatic stellate cells within the
framework of two collaborative research centers CRC575 and CRC974 at the Heinrich …

[HTML][HTML] Cell cycle arrest determines adult neural stem cell ontogeny by an embryonic Notch-nonoscillatory Hey1 module

Y Harada, M Yamada, I Imayoshi, R Kageyama… - Nature …, 2021 - nature.com
Quiescent neural stem cells (NSCs) in the adult mouse brain are the source of neurogenesis
that regulates innate and adaptive behaviors. Adult NSCs in the subventricular zone are …

Microvilli adhesion: an alternative route for nanoparticle cell internalization

P Sommi, A Vitali, S Coniglio, D Callegari, S Barbieri… - ACS …, 2021 - ACS Publications
The cellular uptake of nanoparticles (NPs) represents a critical step in nanomedicine and a
crucial point for understanding the interaction of nanomaterials with biological systems. No …

Neural stem cells in the adult olfactory bulb core generate mature neurons in vivo

Ç Defteralı, M Moreno-Estellés, C Crespo… - Stem Cells, 2021 - academic.oup.com
Although previous studies suggest that neural stem cells (NSCs) exist in the adult olfactory
bulb (OB), their location, identity, and capacity to generate mature neurons in vivo has been …

Maintenance of neural stem-progenitor cells by the lysosomal biosynthesis regulators TFEB and TFE3 in the embryonic mouse telencephalon

N Yuizumi, Y Harada, T Kuniya, T Sunabori… - Stem Cells, 2021 - academic.oup.com
Lysosomes have recently been implicated in regulation of quiescence in adult neural stem
cells (NSCs). Whether lysosomes regulate the differentiation of neural stem-progenitor cells …

Regenerating tubular epithelial cells of the kidney

E Stamellou, K Leuchtle… - Nephrology Dialysis …, 2021 - academic.oup.com
Acute tubular injury accounts for the most common intrinsic cause for acute kidney injury.
Normally, the tubular epithelium is mitotically quiescent. However, upon injury, it can show a …

Histological studies of the ventricular–subventricular zone as neural stem cell and glioma stem cell niche

AA Brockman, BC Mobley… - Journal of Histochemistry …, 2021 - journals.sagepub.com
The neural stem cell niche of the ventricular–subventricular zone supports the persistence of
stem and progenitor cells in the mature brain. This niche has many notable cytoarchitectural …

[HTML][HTML] MAPK signaling is required for generation of tunneling nanotube-like structures in ovarian cancer cells

JM Cole, R Dahl, KD Cowden Dahl - Cancers, 2021 - mdpi.com
Simple Summary Ovarian cancer is the 5th leading cause of cancer death in US women,
due to late diagnosis. The vast majority of patients with ovarian cancer have metastatic …

[HTML][HTML] Commentary: could we address the interplay between CD133, Wnt/β-catenin, and TERT signaling pathways as a potential target for glioblastoma therapy?

CA Fargeas, A Lorico, D Corbeil - Frontiers in Oncology, 2021 - frontiersin.org
We do not intend to analyze here the meaning of the title of the article “Could We Address
the Interplay Between CD133, Wnt/β-Catenin, and TERT Signaling Pathways as a Potential …