Interventions for self‐harm in children and adolescents

KG Witt, SE Hetrick, G Rajaram… - Cochrane database …, 2021 - cochranelibrary.com
Background Self‐harm (SH; intentional self‐poisoning or self‐injury regardless of degree of
suicidal intent or other types of motivation) is a growing problem in most countries, often …

New generation antidepressants for depression in children and adolescents: a network meta‐analysis

SE Hetrick, JE McKenzie, AP Bailey… - Cochrane Database …, 2021 - cochranelibrary.com
Background Major depressive disorders have a significant impact on children and
adolescents, including on educational and vocational outcomes, interpersonal relationships …

The knowns and unknowns of SSRI treatment in young people with depression and anxiety: efficacy, predictors, and mechanisms of action

SE Murphy, LP Capitão, SLC Giles, PJ Cowen… - The Lancet …, 2021 - thelancet.com
The use of SSRIs for the treatment of depression and anxiety in young people is increasing.
However, the effects of SSRIs in adolescence, a time when there are substantial changes in …

Trends in ketamine use, exposures, and seizures in the United States up to 2019

JJ Palamar, C Rutherford… - American journal of …, 2021 - ajph.aphapublications.org
Objectives. To determine whether there have been shifts in nonmedical ketamine use,
poisonings (“exposures”), and seizures. Methods. We used generalized additive models to …

Utility of item 9 of the patient health questionnaire in the prospective identification of adolescents at risk of suicide attempt

RB Penfold, U Whiteside, EE Johnson… - Suicide and Life …, 2021 - Wiley Online Library
Introduction Previous studies report that item 9 of the Patient Health Questionnaire (PHQ9) is
useful for stratifying risk of suicide attempt in adults. This study re‐produced the utility of item …

Prevalence and childhood precursors of opioid use in the early decades of life

L Shanahan, SN Hill, L Bechtiger, A Steinhoff… - JAMA …, 2021 - jamanetwork.com
Importance Opioid use disorder and opioid deaths have increased dramatically in young
adults in the US, but the age-related course or precursors to opioid use among young …

Assessing the benefits of integrating health information exchange services into the medical practices' workflow

K Fecher, L McCarthy, DE Porreca… - Information Systems …, 2021 - Springer
To examine whether integration of Health Information Exchange (HIE) services into office
workflow would have an impact on ED visits and unplanned 30-day readmission amongst …

Enhancing regulatory decision making for postmarket drug safety

V Ahuja, C A. Alvarez, JR Birge… - Management …, 2021 - pubsonline.informs.org
The US Food and Drug Administration (FDA) regulates the approval and safe public use of
pharmaceutical products in the United States. The FDA uses postmarket surveillance …

Effect of the FDA black box suicidality warnings for antidepressants on suicide rates in the USA

M Plöderl, MP Hengartner - Crisis, 2021 - econtent.hogrefe.com
Background: Some authors claimed that the US Food and Drug Administration (FDA) black
box warning on treatment-emergent suicidality with antidepressants in adolescents (issued …

Relationship between suicide rate and antidepressant prescription: An ecological study in the People's Republic of China

Q Xin, D Paudel, L Li, B Zhang… - … Clinical and Experimental, 2021 - Wiley Online Library
Objectives The objective of this study was to estimate the features of suicide rate and its
association with antidepressant prescriptions during the past decade in China. Methods …